Description

Flenox (enoxaparin sodium) solution for injections 2000ME/0.2 ml. №10 syringe

Ingredients

Active ingredient: Enoxaparin sodium

Dosage

Dosage: The usual dose of Flenox is **2000ME/0.2 ml** administered subcutaneously once daily.

Indications

Indications: Flenox is indicated for the prevention of deep vein thrombosis (DVT) in patients undergoing surgery, particularly orthopedic surgery.

Contraindications

Contraindications: Flenox is contraindicated in patients with active major bleeding, hypersensitivity to enoxaparin sodium, or a history of heparin-induced thrombocytopenia.

Directions

Directions: Administer Flenox subcutaneously into the abdomen, alternating sides with each dose. Do not inject into muscle.

Scientific Evidence

Flenox, containing enoxaparin sodium, has been extensively studied for its efficacy in preventing thrombotic events. Clinical trials have demonstrated the superiority of enoxaparin over unfractionated heparin in reducing the risk of DVT and pulmonary embolism post-surgery (Source: The New England Journal of Medicine).

Additional Information

It is important to monitor platelet counts regularly during treatment with Flenox to detect any signs of thrombocytopenia. Patients should be educated on the signs of bleeding and instructed to seek medical attention if they occur.

Pharmacological Effects: Enoxaparin sodium, a low molecular weight heparin, works by enhancing the inhibition of factor Xa and thrombin. This anticoagulant effect prevents the formation of blood clots.

Comparative Effectiveness: Studies have shown that enoxaparin is as effective as unfractionated heparin in preventing DVT but with a lower risk of heparin-induced thrombocytopenia, making it a preferred choice in many clinical settings.