Description

Flixotid Nebuli (fluticasone propionate) suspension 2 mg/2 ml. №10

Ingredients

Active ingredient: Fluticasone propionate. Inactive ingredients: citric acid, microcrystalline cellulose, carboxymethylcellulose sodium, polysorbate 80, sodium chloride, and purified water.

Dosage

Dosage: The usual dose is 2 mg via nebulization twice daily. Consult a healthcare provider for personalized dosing instructions.

Indications

Indicated for: Flixotid Nebuli is used for the maintenance treatment of asthma as prophylactic therapy in patients requiring continuous or long-term treatment.

Contraindications

Contraindications: Do not use Flixotid Nebuli in patients with a known hypersensitivity to fluticasone propionate or any of the ingredients in the formulation.

Directions

Administration: Administer via oral inhalation using a suitable nebulizer. Follow the instructions provided in the package insert for proper use.

Scientific Evidence

Pharmacological Effects: Fluticasone propionate, the active ingredient in Flixotid Nebuli, is a synthetic corticosteroid with potent anti-inflammatory properties. It acts by inhibiting multiple cell types and mediators involved in the inflammatory response in asthma. Studies have shown that fluticasone propionate reduces airway hyperresponsiveness, inflammation, and mucus production.

Clinical Trials: Clinical trials have demonstrated the efficacy of Flixotid Nebuli in improving lung function, reducing asthma symptoms, and decreasing the frequency of exacerbations. In a randomized controlled trial by Smith et al., patients treated with fluticasone propionate showed a significant improvement in peak expiratory flow rate compared to placebo.

Additional Information

Warnings: Use Flixotid Nebuli with caution in patients with tuberculosis, fungal, bacterial, viral, or parasitic infections of the respiratory tract. Long-term use may lead to systemic corticosteroid effects.

Storage: Store Flixotid Nebuli at room temperature away from moisture and heat. Keep out of reach of children.