Description
Flosin (Tamsulosin Hydrochloride) Capsules 0.4 mg. №30
Ingredients
Active ingredient: Tamsulosin hydrochloride 0.4 mg per capsule.
Mechanism of Action
Tamsulosin, the active ingredient in Flosin capsules, is a selective antagonist of alpha-1A adrenergic receptors in the prostate. By blocking these receptors, tamsulosin relaxes the smooth muscles in the bladder neck and prostate, improving urine flow and reducing symptoms of benign prostatic hyperplasia (BPH).
Pharmacological Properties
Tamsulosin hydrochloride exerts its pharmacological effect by specifically targeting alpha-1A adrenergic receptors in the prostate, leading to relaxation of smooth muscles in the urinary tract. This action results in improved urinary flow and reduction of BPH symptoms.
Indications for Use
Flosin capsules are indicated for the treatment of signs and symptoms of benign prostatic hyperplasia (BPH) in adult males.
Contraindications
Flosin capsules are contraindicated in patients with a known hypersensitivity to tamsulosin or any other component of the formulation. Caution should be exercised in patients with a history of orthostatic hypotension.
Side Effects
Common side effects of tamsulosin may include dizziness, headache, abnormal ejaculation, and orthostatic hypotension. Patients should be advised to seek medical attention if they experience severe adverse reactions or allergic responses.
Usage Instructions
Dosage: The recommended dose is 0.4 mg taken orally once daily. It is advisable to administer the capsule approximately 30 minutes after the same meal each day. Swallow the capsule whole with a full glass of water; do not crush, chew, or open it.
Benefits Compared to Analogues
Flosin capsules offer the advantage of targeted alpha-1A receptor blockade, leading to effective relief of BPH symptoms with a reduced risk of systemic side effects compared to non-selective alpha-blockers.
Suitable Patient Groups
Flosin capsules are suitable for adult male patients diagnosed with benign prostatic hyperplasia. Special consideration should be given to elderly patients and those with comorbidities, as they may be more susceptible to the drug’s effects.
Storage and Shelf Life
Store Flosin capsules in a cool, dry place away from direct sunlight. Keep the medication out of reach of children. Check the expiration date on the packaging and do not use the product after the stated shelf life has passed.
Packaging Description
Flosin capsules are available in packs containing 30 capsules. The packaging is designed to maintain the integrity of the capsules and protect them from environmental factors that may affect their potency.
Scientific Evidence
Clinical studies have demonstrated the efficacy of tamsulosin in improving urinary symptoms associated with BPH. A study by Roehrborn et al. (2008) revealed that tamsulosin significantly enhanced peak urine flow rate and symptom scores compared to placebo, supporting its use in the management of BPH.
