Description

Fluconazol-CR (Fluconazole) Capsules 100 mg. №7

Ingredients

Active ingredient: Fluconazole 100 mg.
Other ingredients: lactose monohydrate, maize starch, colloidal anhydrous silica, magnesium stearate, sodium lauryl sulfate, gelatin, titanium dioxide (E171), patent blue V (E131).

Dosage

Adults: The usual dose is one capsule once daily. Consult a healthcare professional for specific dosing instructions.

Indications

Fluconazol-CR Capsules are indicated for the treatment of fungal infections including vaginal candidiasis, oral thrush, esophageal candidiasis, and cryptococcal meningitis.

Contraindications

Do not use Fluconazol-CR Capsules if you are allergic to fluconazole or any other ingredients in the product. Consult your doctor before use if you are pregnant, breastfeeding, or have liver or kidney disease.

Directions

Swallow the capsule whole with a glass of water. It can be taken with or without food. Follow the dosage instructions provided by your healthcare provider.

Scientific Evidence

Fluconazole, the active ingredient in Fluconazol-CR Capsules, is a potent antifungal agent that works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. Studies have shown fluconazole to be effective in treating various fungal infections, with high cure rates and good tolerability.

Additional Information

It is important to complete the full course of treatment as prescribed by your healthcare provider, even if symptoms improve before the treatment is finished. If you experience any severe side effects or allergic reactions, seek medical help immediately.

Pharmacological Effects

Fluconazole exhibits fungistatic activity by specifically inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. This disruption leads to increased permeability and leakage of essential cellular components, ultimately causing fungal cell death. The drug’s selective action on fungal cells minimizes adverse effects on human cells, making it a well-tolerated antifungal agent.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of fluconazole in treating various fungal infections, showing comparable or superior outcomes compared to other antifungal agents. A study published in the Journal of Antimicrobial Chemotherapy found fluconazole to be highly effective in treating candidemia, with a favorable safety profile. The drug’s broad spectrum of activity and convenient dosing regimen make it a preferred choice in the management of fungal infections.