Description

Fluconazol (Fluconazole) Coated Tablets 50 mg. №10

Ingredients:

Each tablet contains 50 mg of fluconazole.

Dosage:

The usual dose is one tablet once daily. Consult your healthcare provider for personalized dosing instructions.

Indications:

Fluconazol tablets are indicated for the treatment of fungal infections including vaginal yeast infections, oral thrush, esophageal candidiasis, and cryptococcal meningitis.

Contraindications:

Do not use Fluconazol tablets if you are allergic to fluconazole or other azole antifungals. Inform your doctor about any existing medical conditions or medications before starting treatment.

Directions:

Swallow the tablet whole with a glass of water. Take as directed by your healthcare provider. It can be taken with or without food.

Scientific Evidence:

Fluconazole, the active ingredient in Fluconazol tablets, is a potent antifungal agent that works by inhibiting the synthesis of ergosterol, a key component of fungal cell membranes. This disruption leads to the death of the fungal cells, effectively treating the infection. Studies have shown the efficacy of fluconazole in treating various fungal infections with a favorable safety profile.

Additional Information:

Fluconazol tablets are well-tolerated by most patients, with common side effects including nausea, headache, and abdominal pain. It is important to complete the full course of treatment as prescribed by your healthcare provider to ensure the infection is fully eradicated. If you experience severe side effects or allergic reactions, seek medical help immediately.

Pharmacological Effects: Fluconazol inhibits the fungal cytochrome P450 enzyme 14α-demethylase, disrupting the synthesis of ergosterol. This action destabilizes the fungal cell membrane, leading to cell death and clearance of the infection.

Clinical Trials: Clinical trials have demonstrated the effectiveness of fluconazole in treating various fungal infections, showing high cure rates and low relapse rates. A study published in the Journal of Antimicrobial Chemotherapy highlighted the efficacy of fluconazole in the treatment of candidemia, a serious bloodstream infection caused by Candida species.