Description

Fluorouracil (fluorouracil) solution for injections 50 mg/ml. 5 ml. (250 mg.) №1

Ingredients:

Fluorouracil (50 mg/ml)

Dosage:

The usual dosage ranges from 12-15 mg/kg/day for 4-5 days, repeated every 3-4 weeks.

Indications:

Fluorouracil is indicated for the treatment of various cancers including colorectal, breast, and gastrointestinal cancers.

Contraindications:

Do not use Fluorouracil if you have a known hypersensitivity to the drug or its components.

Directions:

Administered via intravenous injection by a healthcare professional in a clinical setting.

Scientific Evidence:

Fluorouracil has been extensively studied in various clinical trials for its efficacy in treating different types of cancers. Research published in the Journal of Clinical Oncology has shown that Fluorouracil-based regimens significantly improve survival rates in patients with advanced colorectal cancer.

Additional Information:

Fluorouracil is a pyrimidine analog that inhibits thymidylate synthase, an enzyme essential for DNA synthesis. This action leads to the disruption of cancer cell growth and division, ultimately causing cell death. Compared to other chemotherapy agents, Fluorouracil has shown comparable effectiveness with a more favorable side effect profile in certain cancers.

Clinical trials have demonstrated the benefits of Fluorouracil in combination with other agents in neoadjuvant and adjuvant settings for breast cancer treatment. The drug’s mechanism of action and proven clinical outcomes make it a valuable component in the management of various malignancies.