Description

Fragmin solution for injections 2500 IU 0.2 ml. №10

Ingredients:

Each 0.2 ml ampoule contains 2500 IU of dalteparin sodium as the active ingredient.

Dosage:

The dosage of Fragmin should be individualized based on the patient’s weight, condition, and indication for use. It is usually administered subcutaneously once or twice daily.

Indications:

Fragmin is indicated for the prevention of deep vein thrombosis, treatment of deep vein thrombosis, and prevention of clotting during hemodialysis. It is also used in the treatment of unstable angina and non-Q-wave myocardial infarction.

Contraindications:

Do not use Fragmin in patients with active major bleeding, bacterial endocarditis, or a history of heparin-induced thrombocytopenia. It should also be avoided in patients with a hypersensitivity to dalteparin or pork products.

Directions:

Administer Fragmin by subcutaneous injection into the abdomen, thigh, or upper arm. Rotate injection sites and do not rub the injection site after administration.

Scientific Evidence:

Dalteparin, the active ingredient in Fragmin, is a low molecular weight heparin that exhibits anticoagulant properties by enhancing the inhibition of factor Xa. Studies have shown that dalteparin is effective in preventing venous thromboembolism in various clinical settings, including in patients undergoing surgery and those with cancer.

Additional Information:

Fragmin has been widely studied in clinical trials and has demonstrated efficacy and safety in the prevention and treatment of thrombotic events. It is considered a first-line anticoagulant therapy in many clinical scenarios due to its predictable anticoagulant effect and lower risk of heparin-induced thrombocytopenia compared to unfractionated heparin.

Overall, Fragmin solution for injections 2500 IU 0.2 ml. №10 is a well-established anticoagulant with a proven track record of efficacy and safety in various clinical conditions requiring anticoagulation therapy.