Description

Glibomet Coated Tablets №40

Ingredients

Glibenclamide and Metformin Hydrochloride.

Dosage

The usual dose is one tablet taken orally once or twice daily with meals.

Indications

Glibomet tablets are indicated for the treatment of type 2 diabetes mellitus in adults.

Contraindications

Do not use Glibomet in patients with type 1 diabetes, diabetic ketoacidosis, severe renal impairment, or hypersensitivity to sulfonylureas or biguanides.

Directions

Follow the dosage instructions provided by your healthcare provider. Do not exceed the recommended dose.

Scientific Evidence

Glibomet combines the actions of glibenclamide and metformin to improve glycemic control in patients with type 2 diabetes. Glibenclamide stimulates insulin release from pancreatic beta cells, while metformin reduces hepatic glucose production and improves insulin sensitivity in peripheral tissues.

Clinical trials have shown that the combination of glibenclamide and metformin in Glibomet tablets leads to better glycemic control compared to monotherapy with either drug alone. Additionally, this combination therapy has been associated with a lower risk of hypoglycemia compared to glibenclamide alone.

Additional Information

It is important to monitor blood glucose levels regularly while taking Glibomet tablets to ensure optimal control of diabetes. Adherence to a healthy diet and regular exercise regimen is also essential for the effectiveness of this medication.

Consult your healthcare provider before starting or changing any diabetes medication regimen, including Glibomet tablets. Inform your doctor about any other medications or supplements you are taking to avoid potential drug interactions.