Glicin tablets 100mg №50

Description

Glicin Composition
active substance: glycine;

1 sublingual tablet contains 100 mg glycine;

excipients: mountain wax glycol, ammonium-methacrylate copolymer (type A), calcium stearate.

Glicin Dosage form
Sublingual tablets.

Basic physical and chemical properties: white tablets with beveled and scored.

Glicin Pharmacotherapeutic group
Funds acting on the nervous system.

ATX code N07X X.

Pharmacodynamics
Glycine is a nonessential amino acid. Glycine easily penetrates into biological fluids and body tissues, including the brain, is metabolized; its accumulation in tissues does not occur. It is rapidly destroyed in the liver by glycine oxidase to water and carbon dioxide.

Pharmacokinetics
Glycine is a central neurotransmitter that regulates metabolism, normalizes and activates the processes of protective inhibition in the central nervous system. Improves metabolic processes in brain tissues, has antidepressant and sedative effects. Has glycine and GABA-ergic, α1-adrenergic blocking, antioxidant, antitoxic effects; regulates the activity of glutamate (NMDA) receptors, thereby reducing psycho-emotional stress, aggressiveness and conflict; increases social adaptation, improves mood; facilitates falling asleep and normalizes sleep, increases mental performance, reduces the severity of vegetative-vascular disorders.

L-glycine (glycacol) is involved in the synthesis of substances essential for the body: nucleic acids, glutathione, bile acids, and the like. Glycine is used in the synthesis of porphyrin, the precursor of heme in the hemoglobin molecule, and purine bases, the most important elements of nucleic acids. Glycine is part of the structure of glutathione-containing substances and plays a special role in the anti-radial defense system.

Glycine is involved in detoxification reactions, including in the composition of hippuric acid, as well as in the synthesis of bile acids (glycocholic acid). In addition, glycine is of great importance for the processes of oxalic acid biosynthesis.

Indications
Decreased mental performance. In stressful situations and psychoemotional stress (during exams, in conflict situations). Deviant forms of behavior of children and adults.
Functional and organic diseases of the nervous system (neuroses, neurosis-like states, vegetative-vascular dystonia, the consequence of neuroinfection and traumatic brain injury, perinatal and other forms of encephalopathy, including alcoholic genesis), which are accompanied by increased excitability, emotional instability, decreased mental performance, sleep disturbance.
Ischemic stroke and cerebrovascular accident.
As an adjunct in the treatment of alcoholism.

Contraindications
Individual intolerance to the drug and hypersensitivity to its individual components; arterial hypotension. Age up to 3 years.

Interaction with other medicinal products and other types of interactions
Glycine reduces the toxicity of anticonvulsants, antipsychotics, antidepressants, anticonvulsants. When combined with hypnotics, tranquilizers and antipsychotics, the effect of inhibition of the central nervous system is enhanced.