Description

Gliclazid Tablets 80 mg. №30

Ingredients

Active ingredient: Gliclazide 80mg per tablet.

Dosage

Dosage: The usual dose is 80mg to 320mg daily in divided doses. Consult your healthcare provider for the appropriate dosage for your condition.

Indications

Indications: Gliclazide is indicated for the treatment of type 2 diabetes mellitus when diet, exercise, and weight reduction alone have not been successful.

Contraindications

Contraindications: Do not use Gliclazide if you have type 1 diabetes, diabetic ketoacidosis, severe liver or kidney disease, or a history of a hypersensitivity reaction to sulfonylureas.

Directions

Directions: Take Gliclazide exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Gliclazide, a sulfonylurea antidiabetic agent, works by stimulating the release of insulin from the pancreas, thereby lowering blood sugar levels. Studies have shown that Gliclazide is effective in controlling blood glucose levels in patients with type 2 diabetes. Research published in the Journal of Diabetes Investigation demonstrated the efficacy of Gliclazide in reducing HbA1c levels and improving glycemic control.

Additional Information

It is important to monitor your blood sugar levels regularly while taking Gliclazide to ensure it is effectively managing your diabetes. Inform your doctor of any changes in your health status or if you experience any unusual symptoms while taking this medication.

Pharmacological Effects

Gliclazide acts by binding to specific receptors on the pancreatic beta cells, leading to an increase in insulin secretion. This helps to lower blood sugar levels by facilitating the uptake of glucose into cells for energy production. Additionally, Gliclazide has been shown to have antioxidant properties, which may provide additional benefits in diabetic patients by reducing oxidative stress.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy of Gliclazide in improving glycemic control and reducing the risk of diabetic complications. In comparison to other sulfonylureas, Gliclazide has been reported to have a lower risk of hypoglycemia and cardiovascular events, making it a favorable choice for many patients with type 2 diabetes. Research comparing the effectiveness of Gliclazide with other antidiabetic agents is ongoing to further establish its place in diabetes management.

Overall, Gliclazide tablets 80 mg. №30 offer a reliable treatment option for individuals with type 2 diabetes, backed by scientific evidence and clinical trials supporting its efficacy and safety profile.