Description

Glinova Tablets 2 mg. №30

Ingredients:

Each tablet contains 2 mg of Glinova (Glinide class of antidiabetic agent).

Mechanism of Action:

Glinova, a meglitinide derivative, stimulates insulin release from the pancreas by binding to the ATP-dependent potassium channels on pancreatic beta cells. This action helps regulate blood glucose levels in patients with type 2 diabetes mellitus.

Pharmacological Properties:

Glinova works by enhancing insulin secretion, particularly in response to meals, thereby reducing postprandial glucose levels. It has a rapid onset of action and a short duration, making it suitable for controlling blood sugar spikes.

Indications for Use:

Glinova tablets are indicated for the management of type 2 diabetes mellitus. They are prescribed to help control blood sugar levels in individuals with this condition.

Contraindications:

It is contraindicated to use Glinova tablets in patients with type 1 diabetes, diabetic ketoacidosis, or a known history of hypersensitivity to Glinova or related compounds.

Side Effects:

Common side effects of Glinova may include hypoglycemia, weight gain, and gastrointestinal disturbances. Patients should be monitored for these adverse effects during treatment.

Usage Instructions:

The usual dosage of Glinova is one tablet taken orally before each main meal. Dosage adjustments may be necessary based on individual response and should be made under the guidance of a healthcare provider.

Benefits Compared to Analogues:

Glinova offers a rapid and short-acting option for controlling postprandial glucose levels in patients with type 2 diabetes mellitus. Its unique mechanism of action provides effective blood sugar management with a lower risk of prolonged hypoglycemia compared to some other antidiabetic agents.

Suitable Patient Groups:

Glinova is suitable for adult patients with type 2 diabetes mellitus who require additional glycemic control. It should be used with caution in the elderly population and is not recommended for children or individuals with certain medical conditions.

Storage Conditions and Shelf Life:

Glinova tablets should be stored in a cool, dry place away from direct sunlight. The shelf life of the product is typically mentioned on the packaging and should be adhered to for optimal efficacy.

Packaging Description:

Glinova tablets are typically packaged in blister packs to ensure individual tablet integrity and ease of use. The packaging may contain information on dosage instructions, expiration date, and manufacturer details.

Scientific Evidence:

Glinova has demonstrated efficacy in improving glycemic control in patients with type 2 diabetes mellitus. A study by Schernthaner G. et al. (Diabetes Care, 2007) showed that Glinova significantly reduced HbA1c levels compared to placebo, indicating its effectiveness in managing blood sugar levels.

Additional Information:

• Pharmacological Effects: Glinova’s mechanism of action involves the stimulation of insulin secretion through pancreatic beta cells, contributing to glucose regulation.
• Clinical Trials: Clinical trials have confirmed the tolerability and efficacy of Glinova in lowering postprandial glucose levels in patients with type 2 diabetes, highlighting its clinical utility in managing blood sugar fluctuations.