Description
Gliucofaj Coated Tablets 1000 mg. №30
Ingredients:
Each coated tablet contains 1000 mg of Metformin Hydrochloride.
Mechanism of Action:
Gliucofaj works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, thereby lowering blood sugar levels in patients with type 2 diabetes mellitus.
Pharmacological Properties:
Metformin, the active ingredient in Gliucofaj, belongs to the biguanide class of antidiabetic medications. It reduces hepatic glucose production, increases glucose uptake by muscles, and improves insulin sensitivity.
Indications for Use:
Gliucofaj tablets are indicated for the treatment of type 2 diabetes mellitus in adults. They are used to improve glycemic control and reduce the risk of complications associated with high blood sugar levels.
Contraindications:
Do not use Gliucofaj if you have severe renal impairment, metabolic acidosis, or a history of lactic acidosis. It is contraindicated in patients with acute or chronic metabolic acidosis, including diabetic ketoacidosis.
Side Effects:
Common side effects of Gliucofaj include gastrointestinal symptoms such as diarrhea, nausea, and abdominal discomfort. In rare cases, it may cause lactic acidosis, a serious but rare metabolic complication.
Usage Instructions:
Take Gliucofaj tablets as prescribed by your healthcare provider. The usual starting dose is 500 mg or 850 mg once daily with meals, gradually increasing the dose based on blood glucose levels.
Benefits Compared to Analogues:
Gliucofaj offers the advantage of improving insulin sensitivity without causing weight gain, unlike some other antidiabetic medications. Its established safety profile and cardiovascular benefits make it a preferred choice for many patients.
Suitable Patient Groups:
Gliucofaj is suitable for adult patients with type 2 diabetes mellitus who require pharmacological intervention to control their blood sugar levels. It is not recommended for use in children, pregnant women, or individuals with type 1 diabetes.
Storage and Shelf Life:
Store Gliucofaj in a cool, dry place away from moisture and heat. Keep the tablets in their original packaging to protect them from light. Check the expiration date on the packaging and do not use the product beyond this date.
Packaging Description:
Gliucofaj tablets are supplied in blister packs containing 30 coated tablets. Each tablet is imprinted with the product name and strength for easy identification.
Clinical Evidence and Proven Effectiveness:
Studies have demonstrated the efficacy of Metformin in improving glycemic control and reducing cardiovascular risk factors in patients with type 2 diabetes mellitus. Clinical trials have shown that Metformin therapy is associated with a decreased incidence of macrovascular complications.
Additional Information:
Regular monitoring of renal function is essential during Gliucofaj therapy to detect any early signs of kidney impairment. If you experience persistent or severe side effects while taking this medication, consult your healthcare provider promptly for further evaluation and management.
