Description
Gliucofaj Coated Tablets 1000 mg. №60
Ingredients:
Each coated tablet contains 1000 mg of Glucophage (Metformin Hydrochloride).
Mechanism of Action:
Metformin, the active ingredient in Gliucofaj tablets, works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, leading to reduced blood sugar levels.
Pharmacological Properties:
Metformin belongs to the biguanide class of antidiabetic medications. It lowers both basal and postprandial plasma glucose levels without causing hypoglycemia. Additionally, metformin has been associated with modest weight loss in diabetic patients.
Indications for Use:
Gliucofaj tablets are indicated for the treatment of type 2 diabetes mellitus in adults and children over 10 years of age. They are particularly beneficial for individuals who require improvement in glycemic control.
Contraindications:
Avoid using Gliucofaj tablets in patients with renal impairment, metabolic acidosis, or a known hypersensitivity to metformin. These conditions may predispose individuals to serious adverse effects.
Side Effects:
- Common side effects may include gastrointestinal disturbances such as diarrhea, nausea, and abdominal discomfort.
- Rare but serious side effects can include lactic acidosis, a potentially life-threatening condition.
Usage Instructions:
Take one tablet orally with meals, once or twice daily, as prescribed by a healthcare provider. Swallow the tablets whole with a full glass of water. Do not crush or chew the tablets to ensure proper absorption.
Benefits Compared to Analogues:
Gliucofaj tablets offer the advantage of proven efficacy in managing blood sugar levels with a lower risk of hypoglycemia compared to some other antidiabetic medications. Additionally, metformin has shown cardiovascular benefits beyond glycemic control.
Suitable Patient Groups:
Gliucofaj tablets are suitable for both adult and pediatric patients over 10 years old with type 2 diabetes. The dosage may need adjustment in elderly individuals or those with renal impairment, requiring close monitoring.
Storage and Shelf Life:
Store Gliucofaj tablets in a cool, dry place away from direct sunlight. Check the expiration date on the packaging and do not use the tablets beyond the specified shelf life.
Packaging Description:
Gliucofaj tablets are supplied in a blister pack containing 60 coated tablets. The packaging is designed to protect the tablets from moisture and ensure their stability until the expiration date.
Scientific Evidence:
Metformin has been extensively researched for its efficacy in managing blood sugar levels in patients with type 2 diabetes. Studies have shown that metformin significantly reduces hemoglobin A1c levels, indicating improved long-term glucose control.
Clinical trials have also demonstrated that metformin may reduce the risk of cardiovascular events in diabetic patients. Research suggests that metformin use is associated with a lower incidence of cardiovascular disease compared to other antidiabetic medications.
Additional Information:
Regular monitoring of renal function is crucial while taking Gliucofaj tablets, especially in patients with impaired kidney function. Consult a healthcare provider before initiating or adjusting the dosage to minimize the risk of lactic acidosis.
For optimal results in managing type 2 diabetes, Gliucofaj tablets should be used in conjunction with dietary modifications and regular exercise. Follow the recommendations provided by your healthcare team to achieve better glycemic control and overall health outcomes.
