Description

Gliucofaj XR Tablets with Prolonged Release 500 mg. №30

Ingredients:

Each tablet contains 500 mg of Metformin Hydrochloride.

Dosage:

The recommended dose is one tablet daily with a meal or as directed by a healthcare professional.

Indications:

Gliucofaj XR tablets are indicated for the management of type 2 diabetes mellitus.

Contraindications:

Do not use Gliucofaj XR tablets in patients with renal impairment, metabolic acidosis, or hypersensitivity to metformin.

Directions:

Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.

Scientific Evidence:

Studies have shown that Metformin, the active ingredient in Gliucofaj XR tablets, works by decreasing glucose production in the liver and improving insulin sensitivity in the body. This helps to lower blood sugar levels and control diabetes effectively.

Pharmacological Effects:

Metformin belongs to the biguanide class of drugs and is the first-line medication for the treatment of type 2 diabetes. It works by reducing the amount of sugar produced by the liver and increasing the sensitivity of muscle cells to insulin, allowing for better glucose uptake and utilization.

Clinical Trials:

In a randomized controlled trial published in the New England Journal of Medicine, Metformin was found to be more effective in reducing cardiovascular events and mortality in diabetic patients compared to other antidiabetic medications. The study highlighted the cardioprotective benefits of Metformin beyond its glucose-lowering effects.

Additional Information:

• Storage: Store at room temperature away from moisture and heat.
• Side Effects: Common side effects may include diarrhea, nausea, and stomach upset.
• Warnings: Consult a healthcare provider before using Gliucofaj XR tablets if pregnant or breastfeeding.