Description
Hartil-N (Ramipril + Hydrochlorothiazide) Tablets 2.5 mg/12.5 mg. №28
Ingredients
Each Hartil-N tablet contains 2.5 mg of ramipril and 12.5 mg of hydrochlorothiazide.
Mechanism of Action
Ramipril is an angiotensin-converting enzyme (ACE) inhibitor that reduces the production of angiotensin II, leading to vasodilation and decreased aldosterone secretion. Hydrochlorothiazide is a thiazide diuretic that inhibits sodium reabsorption in the distal convoluted tubule, promoting diuresis and reducing blood volume.
Pharmacological Properties
Hartil-N combines the antihypertensive effects of ramipril with the diuretic properties of hydrochlorothiazide, resulting in a synergistic reduction of blood pressure. Ramipril helps relax blood vessels, while hydrochlorothiazide increases urine output, collectively aiding in the management of hypertension.
Indications for Use
Hartil-N is indicated for the treatment of hypertension. It is suitable for both initial therapy and as an adjunct to other antihypertensive agents.
Contraindications
Hartil-N is contraindicated in patients with known hypersensitivity to any component of the product. It should not be used in individuals with severe renal impairment or hepatic dysfunction due to the risk of further organ damage.
Side Effects
Common side effects of Hartil-N may include dizziness, cough, hypotension, electrolyte imbalances, and renal dysfunction. Patients should seek medical attention if they experience severe or persistent adverse reactions.
Usage Instructions
The recommended dosage of Hartil-N is one tablet per day, to be taken orally with a glass of water, preferably in the morning. It is important not to exceed the prescribed dose to avoid potential complications.
- Do not double up on doses.
- Do not discontinue Hartil-N without consulting your healthcare provider.
Benefits Compared to Analogues
Hartil-N offers the advantage of combining two different classes of antihypertensive agents in a single tablet, providing a convenient and effective treatment option for individuals with hypertension. This combination therapy can lead to improved blood pressure control compared to using each drug separately.
Suitable Patient Groups
Hartil-N is suitable for adult patients with hypertension, including the elderly population. However, special caution should be exercised when prescribing to individuals with impaired renal or hepatic function. It is not recommended for use in children due to limited safety data in this age group.
Storage and Shelf Life
Hartil-N should be stored at room temperature, away from moisture and heat. The tablets should be kept in their original packaging to protect them from light. The shelf life of the product is typically indicated on the packaging and should be checked before use.
Packaging Description
Hartil-N is supplied in blister packs containing 28 tablets. Each tablet is individually sealed to maintain product integrity and ensure dosage accuracy. The packaging should be inspected for any signs of tampering before use.
