Description
Hartil-N Tablets: A Comprehensive Medication for Hypertension
Composition
The active ingredients in Hartil-N tablets are ramipril and hydrochlorothiazide. Each tablet contains 5 mg of ramipril and 25 mg of hydrochlorothiazide.
Mechanism of Action
Ramipril, an angiotensin-converting enzyme (ACE) inhibitor, works by inhibiting the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced aldosterone secretion. Hydrochlorothiazide, a thiazide diuretic, promotes diuresis by inhibiting sodium reabsorption in the distal convoluted tubule.
Pharmacological Properties
Hartil-N combines the antihypertensive effects of ramipril with the diuretic actions of hydrochlorothiazide, resulting in effective blood pressure control. Ramipril also offers cardioprotective benefits beyond blood pressure reduction.
Indications for Use
Hartil-N is indicated for the treatment of hypertension (high blood pressure). It can be used as monotherapy or in combination with other antihypertensive agents to achieve optimal blood pressure control.
Contraindications
- Patients with known hypersensitivity to ramipril, hydrochlorothiazide, or any other component of Hartil-N should avoid its use.
- It is contraindicated in individuals with severe renal impairment, hepatic dysfunction, and anuria due to the diuretic component.
- Pregnant women, especially in the second and third trimesters, and nursing mothers should not take Hartil-N due to potential risks to the fetus or infant.
Side Effects
Common side effects of Hartil-N may include dizziness, cough, hypotension, electrolyte imbalances, and renal dysfunction. Monitoring of renal function and electrolytes is recommended during therapy.
Usage Instructions
The recommended dosage of Hartil-N is one tablet daily, to be taken orally with a full glass of water. It is advisable to take the medication at the same time each day to maintain consistent drug levels in the body.
Patients should not alter the dosage without medical supervision, and regular blood pressure monitoring is essential during treatment.
Benefits over Analogues
Hartil-N offers the advantage of dual therapy in a single tablet, combining the benefits of an ACE inhibitor and a diuretic in one convenient dose. This simplifies treatment regimens and enhances patient compliance.
Suitable Patient Groups
Hartil-N is suitable for adult patients with hypertension, including the elderly population. However, caution should be exercised in patients with impaired renal or hepatic function, and dosage adjustments may be necessary in these cases.
Storage and Shelf Life
Hartil-N should be stored in a cool, dry place away from direct sunlight. The tablets should be kept in their original packaging to protect them from moisture. The shelf life of the product is typically mentioned on the packaging and should be adhered to for optimal efficacy.
Packaging Description
Hartil-N tablets are typically packaged in blister packs to ensure individual tablet integrity and facilitate easy daily dispensing. Each pack contains a specified number of tablets, as indicated by the prescription.
Clinical Evidence and Proven Effectiveness
No specific clinical studies have been referenced to demonstrate the efficacy of Hartil-N. However, the individual components, ramipril, and hydrochlorothiazide, have been extensively studied and proven effective in the management of hypertension and related cardiovascular conditions.
