$8.00
Manufacturer: Poland
Symptomatic treatment of fever and pain of various origins in children aged 6 months to 12 years with a body weight of at least 8 kg (including fever after immunization, acute respiratory viral infections, influenza, teething pain, pain after tooth extraction, toothache, headache
Description
Ibufen forte Composition
active substance: ibuprofen;
5 ml of suspension contains 200 mg ibuprofen;
excipients: hypromellose, xanthan gum, glycerin, sodium benzoate (E 211), citric acid, sodium, sodium saccharin, liquid maltitol, sodium chloride, strawberry or raspberry flavor, purified water.
Ibufen forte Dosage form
Oral suspension with raspberry or strawberry flavor.
Basic physical and chemical properties: suspension of white or almost white color with homogeneous opalescence and with a strawberry or raspberry smell.
Ibufen forte Pharmacotherapeutic group
Non-steroidal anti-inflammatory drugs and anti-inflammatory drugs derived from propionic acid. ATX code М01А Е01.
Pharmacodynamics
Ibuprofen is an NSAID (NSAID) derivative of propionic acid that has been shown to be effective by inhibiting the synthesis of prostaglandins, which mediate pain and inflammation. Ibuprofen has analgesic, antipyretic and anti-inflammatory effects. In addition, ibuprofen reversibly inhibits platelet aggregation.
The clinical efficacy of ibuprofen has been demonstrated during symptomatic treatment of mild to moderate pain such as toothache, headache, and symptomatic treatment of fever.
The analgesic dose for children is from 7 to 10 mg / kg body weight with a maximum use of 30 mg / kg / day. The medicinal product contains ibuprofen. In an open study, the onset of the antipyretic effect of the drug was recorded 15 minutes after its use, the temperature decrease in children continued for a period of up to 8 hours.
Pharmacokinetics
Special studies of pharmacokinetics with the participation of children have not been carried out. Published data confirm that absorption, metabolism and excretion of ibuprofen in children is the same as in adults.
After oral administration, ibuprofen is partially absorbed in the stomach, after which it is completely absorbed in the small intestine. After metabolism in the liver (hydroxylation, carboxylation, conjugation), inactive metabolites are excreted completely, mainly by the kidneys (90%), as well as with bile. The half-life in healthy volunteers, as well as in patients with kidney or liver disease, is from 1.8 to 3.5 hours. Plasma protein binding is about 99%.
Indications
Symptomatic treatment of fever and pain of various origins in children aged 6 months to 12 years with a body weight of at least 8 kg (including fever after immunization, with acute respiratory viral infections, influenza, pain during teething, pain after tooth extraction, toothache , headache, sore throat, pain with sprains and other types of pain, including inflammatory genesis).
Contraindications
Highernnaya sensitivity to ibuprofen or to any of the components of the drug.
A history of hypersensitivity reactions (eg, bronchospasm, asthma, rhinitis, angioedema or urticaria) after using ibuprofen, acetylsalicylic acid, or other NSAIDs.
Peptic ulcer and duodenal ulcer / bleeding in active form or relapses in history (two or more severe episodes of confirmed peptic ulcer or bleeding).
A history of gastrointestinal bleeding or perforation associated with taking NSAIDs.
Active inflammatory bowel disease.
Cerebrovascular or other bleeding.
Hemorrhagic diathesis or other bleeding disorders.
Severe heart failure (NYHA class IV), severe liver failure, or severe renal failure.
The last trimester of pregnancy.
Severe dehydration (due to vomiting, diarrhea, or insufficient fluid intake).
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