Description

Indapamid-TEVA Composition

active substance: indapamide 1 tablet contains 1.5 mg indapamide
excipients: lactose, hypromellose, colloidal silicon dioxide, magnesium stearate, glycerin, titanium dioxide (E 171).

Indapamid-TEVA Dosage form

Sustained-release film-coated tablets.

Indapamid-TEVA Pharmacological group

Drugs affecting the cardiovascular system. Moderately active non-thiazide diuretics. Indapamide. ATC code С0ЗВ А11.

Indications

Essential hypertension.

Indapamid-TEVA Contraindications

Hypersensitivity to indapamide, other sulfonamides, or to any other components of the drug
severe liver dysfunction and hepatic encephalopathy
severe renal failure
hypokalemia.
Method of administration and dosage

For oral administration: 1 tablet daily, preferably in the morning. The tablets should be swallowed whole without chewing with water.

The maximum daily dose is 1.5 mg of indapamide (1 tablet). An increase in the dose of the drug does not lead to an increase in the antihypertensive effect, but leads to an increase in its diuretic effect.

In elderly patients, plasma creatinine levels should be appropriate for age, body weight and gender. Elderly patients can be prescribed indapamide if renal function is not impaired or if the impairment is insignificant.

In case of severe liver dysfunction, treatment is contraindicated.

The duration of treatment is determined by the doctor individually.

Adverse Reactions

Most of the side effects, both clinical and laboratory parameters, are dose-dependent. Thiazide-like diuretics, including indapamide, can cause the side effects listed below.

From the blood and lymphatic system: thrombocytopenia, leukopenia, agranulocytosis, aplastic anemia, hemolytic anemia.

From the immune system: hypersensitivity reactions, mainly dermatological reactions, especially in patients prone to allergic and asthmatic reactions.

Metabolic disorders:

hypercalcemia, hypokalemia.

Hyponatremia with hypovolemia can lead to dehydration and orthostatic hypotension. The concomitant loss of chlorine ions can cause secondary compensatory metabolic alkalosis. An increase in the level of uric acid and glucose in the blood plasma during treatment with thiazide diuretics is possible: the advisability of prescribing these diuretics in patients with gout and diabetes mellitus should be weighed.

From the nervous system: dizziness, fatigue, headache, paresthesia, fainting.