Description
Indobrest Capsules №30
Ingredients
Each capsule contains:
- Indomethacin 25mg
- Bromelain 100mg
- Trypsin 48mg
Mechanism of Action
The combination of indomethacin, bromelain, and trypsin in Indobrest Capsules №30 provides a synergistic effect in reducing pain and inflammation. Indomethacin, a nonsteroidal anti-inflammatory drug (NSAID), inhibits prostaglandin synthesis. Bromelain and trypsin possess anti-inflammatory and analgesic properties that complement the action of indomethacin.
Pharmacological Properties
Indomethacin acts by inhibiting cyclooxygenase enzymes, thereby reducing the production of prostaglandins involved in inflammation. Bromelain and trypsin exert their effects by modulating inflammatory pathways and promoting tissue repair.
Indications for Use
Indobrest Capsules №30 are indicated for the relief of pain and inflammation associated with arthritis, musculoskeletal disorders, and postoperative conditions.
Contraindications
Do not use Indobrest Capsules №30 if you have a history of hypersensitivity to any of the ingredients or if you are pregnant.
Side Effects
Common side effects may include gastrointestinal disturbances, dizziness, and skin reactions. If you experience any severe or persistent side effects, discontinue use and consult a healthcare provider.
Usage Instructions
Adults: Take 1 capsule three times daily with meals or as directed by a healthcare professional. Swallow the capsules whole with a full glass of water. Do not crush or chew the capsules.
Benefits Compared to Analogues
The unique combination of indomethacin, bromelain, and trypsin in Indobrest Capsules №30 offers a comprehensive approach to managing pain and inflammation, providing enhanced efficacy compared to single-agent formulations.
Suitable Patient Groups
Indobrest Capsules №30 are suitable for use in adult patients. Consult a healthcare provider for appropriate dosing in specific populations such as the elderly or individuals with renal or hepatic impairment.
Storage and Shelf Life
Store Indobrest Capsules №30 in a cool, dry place away from direct sunlight. Ensure the product is kept out of reach of children. Check the expiration date on the packaging and do not use the capsules beyond this date.
Packaging Description
Indobrest Capsules №30 are available in blister packs containing 30 capsules. Each capsule is individually sealed to maintain product integrity and potency.
Clinical Evidence and Proven Effectiveness
Studies have shown that the combination of indomethacin, bromelain, and trypsin in Indobrest Capsules №30 provides effective relief of pain and inflammation. Research published in the Journal of Alternative and Complementary Medicine demonstrated the efficacy of bromelain and trypsin in improving joint function and reducing edema in patients with osteoarthritis. The addition of indomethacin enhances the overall anti-inflammatory effect of the capsules.
