Inflarax ointment 50 g.

Description

Inflarax 50 g Pharmacological properties
Pharmacodynamics. the ointment has anti-inflammatory, analgesic and antimicrobial effects. amikacin and benzalkonium chloride have a broad spectrum of antimicrobial activity against gram-positive and gram-negative microorganisms, including staphylococci, Pseudomonas aeruginosa and Escherichia coli. the mechanism of action is due to the ability to bind to ribosomes, which leads to irreversible inhibition of protein synthesis, to fix on the cytoplasmic membranes of bacteria, disrupting their permeability, while the cell loses potassium ions, amino acids, nucleotides. Nimesulide has an anti-inflammatory (suppresses the inflammation phase due to a decrease in the activity of inflammatory mediators, which helps to reduce the permeability of the vascular wall) and an analgesic effect (a decrease in tissue edema is accompanied by a decrease in the severity of pain), and lidocaine has a local anesthetic effect (due to the membrane stabilizing effect, the action potential decreases). the water-soluble base of the ointment – polyethylene oxide – enhances and prolongs its antibacterial and anti-inflammatory effect, has a pronounced and long-term osmotic effect. thus, when applying the ointment, perifocal edema is eliminated and the wound is cleared of purulent-necrotic contents. the therapeutic activity lasts for 20-24 hours.

Inflarax 50 g Pharmacokinetics.

Has not been studied.

Inflarax 50 g Indications
In surgical practice, the drug is used to treat purulent wounds in the і (purulent-necrotic) phase of the wound process; postoperative complications (postoperative wound suppuration, phlegmon, fistula, abscess); for the prevention of suppuration of superficial and deep wounds; in combustiology – for the prevention and treatment of suppuration of burn wounds; in dermatology for the treatment of purulent-inflammatory skin diseases (pyoderma).

Application
The ointment is applied in a thin layer to the affected areas 1-2 times a day or soaked in sterile gauze wipes, which are applied to the wound. the required amount of the drug is determined by the area of ​​the wound surface and the degree of purulent exudation. the ointment should cover the entire affected area.

In the treatment of purulent wounds, purulent-inflammatory skin diseases, the ointment is used daily.

In the treatment of burns – daily or 2-3 times a week, depending on the amount of purulent discharge.

The duration of the course of treatment is determined individually, depending on the effectiveness of therapy and the size of the damage. Dressings with ointment are used until the wound is completely cleared of the purulent-necrotic process, but no more than 5-7 days.

Contraindications
Hypersensitivity to any of the components of the drug, psoriasis, eczema, fungal skin lesions. children under 2 years of age.