Inspiron coated tablets 80 mg. №30

Description

INSPIRON TABLETS STORAGE
active substance: 1 tablet contains fenspiride hydrochloride, in terms of 100% substance, 80 mg

Excipients: calcium hydrogen phosphate, hypromellose dihydrate (hydroxypropylmethylcellulose) povidone silicon dioxide colloidal anhydrous magnesium stearate coating mixture & laquo Opadry II WHITE & raquo 33G28707 (hypromellose (hydroxypropylmethylcetyl)

INSPIRON TABLETS PHARMACEUTICAL FORM
Film-coated tablets.

INSPIRON TABLETS  MAIN PHYSICO-CHEMICAL PROPERTIES:
tablets, film-coated white, round, with a biconvex surface. The fault shows a white or almost white nucleus.

PHARMACOTHERAPEUTIC GROUP
Agents acting on the respiratory system. Other agents for systemic use in obstructive airways diseases.

ATX code R03D X03.

PHARMACOLOGICAL PROPERTIES
Pharmacodynamics

Inspiron & reg has anti-bronchoconstrictor and anti-inflammatory properties due to the interaction of several interrelated mechanisms:

blocks H1-histamine receptors and has an antispasmodic effect on bronchial smooth muscle
has an anti-inflammatory effect, which reduces the production of various anti-inflammatory factors (cytokines, TNF-a, arachidonic acid derivatives, prostaglandins, leukotrienes, thromboxane, free radicals), some of them
also have a bronchoconstrictor effect
inhibits α-1-adrenoceptors, which stimulate the secretion of viscous mucus.
Pharmacokinetics.

The maximum concentration in blood plasma is reached on average in 6 hours after oral administration. The half-life & ndash 12 hours. Fenspiride is excreted mainly in the urine.

INDICATION
Treatment of acute and chronic inflammatory processes of the ENT organs and respiratory tract (otitis, sinusitis, rhinitis, rhinopharyngitis, tracheitis, rhinotracheobronchitis, bronchitis), chronic obstructive pulmonary disease (COPD), as part of complex therapy of bronchial asthma.
Seasonal and perennial allergic rhinitis and other manifestations of allergies from the respiratory system and ENT organs.
Respiratory manifestations of measles, influenza.
Symptomatic treatment of whooping cough.

CONTRAINDICATION
Hypersensitivity (allergy) to the active substance or to any of the components of the drug.