Insular Stabil suspension for injections 100 IU/ml. 3 ml. cartridge №5

Description

Insular Stabil Storage:
active substance: 1 ml of suspension contains 100 IU of recombinant human insulin;
Excipients: protamine sulphate, sodium hydrogen phosphate dihydrate, glycerin, metacresol, phenol, water for injections.

Insular Stabil Dosage form.

Suspension for injection.
Main physical and chemical properties: white suspension. When standing, the suspension settles. The liquid above the precipitate is clear, colorless or almost colorless. The precipitate is easily resuspended by light shaking.

Insular Stabil Pharmacotherapeutic group.

Antidiabetic drugs. Insulin and analogues of medium duration of action. ATX code A10A C01.

Pharmacological properties.
Pharmacodynamics. The main effect of insulin is to regulate glucose metabolism. In addition, insulin affects some anabolic and anticatabolic processes in various tissues. In muscle tissue, such effects include increased synthesis of glycogen, fatty acids, glycerol and protein, as well as increased amino acid uptake, impaired glycogenolysis, neoglucogenesis, ketogenesis, lipolysis, protein catabolism and amino acid removal.
Pharmacokinetics. Insular Stable is a medium-acting insulin.
Insular Stable is a human insulin that is prepared using recombinant DNA technology.
The pharmacokinetics of insulin do not reflect the metabolic activity of the hormone.
The time of onset of effect of the drug Insular Stabil – 1-2 hours after administration. Peak concentrations occur between 6 and 12 hours after injection. The duration of the hypoglycemic effect is 18-24 hours.

Clinical characteristics.
Indication. Treatment of diabetes.

Contraindication.

Hypoglycaemia, hypersensitivity to Insular Stabil and any of its components, except in cases of desensitizing therapy.

Features of application.
Use during pregnancy or breastfeeding. Insulin requirements usually decrease during the first trimester of pregnancy and then increase during the second and third trimesters. Women with diabetes should tell their doctors if they are pregnant or planning to become pregnant. Careful monitoring of blood glucose and general health is vital for pregnant women with diabetes.
Women with diabetes may need to adjust their insulin dose and / or diet during breastfeeding.