$5.00
Manufacturer: Ukraine
potassium iodide? Some forms of iodine help your thyroid work properly. Most people get the iodine they need from foods like iodized salt or fish. The thyroid can “store” or retain only a certain amount of iodine. In the event of a radiation emergency, radioactive iodine may be released into the air. This material can be inhaled or swallowed. It can get into the thyroid gland and damage it. The damage probably won’t show for years. Children most often have thyroid damage. If you take potassium iodide, it will fill the thyroid gland. This reduces the likelihood of harmful radioactive iodine entering the thyroid gland.
Description
Iodid tablets Storage
active substance: potassium iodide;
1 tablet contains potassium iodide in terms of dry matter 130.8 μg or 261.6 μg and iodine 100 μg or 200 μg;
Excipients: lactose monohydrate, microcrystalline cellulose, heavy magnesium carbonate, sodium thiosulfate, colloidal anhydrous silica, povidone, magnesium stearate.
Iodid tablets Dosage form
Tablets.
Main physical and chemical properties: tablets white or white with a yellowish tinge, with a flat surface, a dash and a bevel.
Iodid tablets Pharmacotherapeutic group
Drugs for the treatment of thyroid diseases. Thyroid drugs. Iodine preparations.
ATX code H0ZS A.
Pharmacological properties
Pharmacodynamics
Iodide-Farmak® is a preparation of inorganic iodine. Iodine is a vital trace element that is part of the thyroid hormones – thyroxine (T4) and triiodothyronine (T3), which ensures its normal functioning.
When iodides enter the epithelial cells of the thyroid follicles under the influence of the enzyme iodide peroxidase, iodine is oxidized to form elemental iodine. The substance undergoes a substitution reaction with the aromatic cycle of tyrosine, resulting in the formation of tyronines: 3,5-iodine derivative (hormone thyroxine – T4) and 3-iodine derivative (hormone triiodothyronine – T3). Tyronines form a complex with the protein thyroglobulin, which is deposited in the colloid of the thyroid follicle and stored in this state for several days and weeks. With iodine deficiency, this process is disrupted. Iodine, which enters the body in physiological quantities, prevents the development of endemic goiter associated with a lack of this element in food; normalizes the size of the thyroid gland in newborns, children, adolescents and young adult patients; affects the ratio of T3 / T4, the level of TSH.
Pharmacokinetics
After oral administration, iodine is almost completely absorbed in the small intestine. Within 2 hours after absorption, it is distributed in the intercellular space; accumulates in the thyroid gland, kidneys, stomach, mammary and salivary glands. The volume of distribution in a healthy person averages 23 liters (38% of body weight). The concentration in blood plasma after the application of a standard dose is 10 – 50 ng / ml, while the content of iodine in breast milk, saliva, gastric juice is 30 times higher than the concentration in blood plasma. The thyroid gland contains ¾ (10 – 20 mg) of all iodine in the body. Iodine is excreted mainly in the urine, to a lesser extent in the feces and exhaled air. When the equilibrium concentration is reached, the amount of iodine excreted is proportional to the daily intake with food.
Indication
Prevention of iodine deficiency, including during pregnancy or breastfeeding.
Prevention of recurrence of iodine-deficient goiter after surgical treatment, as well as after completion of complex treatment with thyroid hormones.
Treatment of diffuse euthyroid iodine deficiency goiter in children, including newborns and adults.
Contraindication
Hypersensitivity or a history of hypersensitivity to the active substance or other components of the drug. Severe hyperthyroidism. Latent hyperthyroidism in doses exceeding 150 mcg of iodine per day. The presence of autonomic adenoma, as well as focal and diffuse autonomic foci of the thyroid gland at a dose of 300 to 1000 mcg of iodine per day (except for preoperative iodine therapy to block the thyroid gland according to Plummer). Pulmonary tuberculosis. Hemorrhagic diathesis. Duhring’s herpetiform dermatitis (Duhring-Brock syndrome).
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