$5.00
Manufacturer: Ukraine
Applied externally as an antiseptic, irritant for infectious and inflammatory diseases of the skin and mucous membranes, for the treatment of the operating field, for the prevention of infection of small damage to the integrity of the skin, to reduce inflammatory processes in myositis, neuralgia (has a distracting effect).
Description
Iodine solution Composition
active substance:
1 ml contains 100 mg of povidone iodine
Excipients:
IODINE SOLUTION DOSAGE FORM
Solution for external and local use.
Basic physical and chemical properties:
IODINE SOLUTION PHARMACOLOGICAL GROUP
ATX code D08A G02.
PHARMACOLOGICAL PROPERTIES
Pharmacological.
Mechanism of action: free iodine has a fast bactericidal effect, and the polymer is a depot for iodine.
On contact with skin and mucous membranes, a significant amount of iodine is released from the polymer.
When a complex is formed with PVP, iodine largely loses the local irritating effect inherent in an alcoholic solution of iodine, and therefore is well tolerated by the skin, mucous membranes and affected surfaces.
The active substance of the drug Betadine cutaneous solution has a wide antimicrobial spectrum of action, namely, it acts on gram-positive and gram-negative bacteria (bactericidal), viruses (virucidal), fungi (fungicidal) and fungal spores (sporicidal), as well as some simple microorganisms ( protozoal).
Due to the mechanism of action, resistance to betadine, including secondary resistance, is not expected with long-term use.
Betadine is water soluble and can be easily washed off with water.
In patients with normal thyroid function, an increase in iodine stores does not cause clinically significant changes in thyroid hormonal status.
Pharmacokinetics
Absorption and renal excretion of povidone-iodine depends on its molecular weight, and since it ranges from 35,000 to 50,000, the substance may be retained.
Betadine is excreted from the body mainly through the kidneys with a clearance of 15 to 60 ml / min, depending on the level of iodine in the blood plasma and creatinine clearance (normal: 100-300 μg of iodine per 1 g of creatinine).
Indications
Hand disinfection and antiseptic treatment of mucous membranes, for example, before surgery, gynecological and obstetric procedures, bladder catheterization, biopsy, injections, punctures, blood sampling, as well as first aid in case of accidental contamination of the skin with infected material.
Antiseptic treatment of wounds and burns.
Hygienic and surgical hand disinfection.
Contraindications
Hypersensitivity to iodine or suspicion of it or other components of the betadine drug.
Patients with impaired thyroid function (nodular colloid goiter, endemic goiter and Hashimoto’s thyroiditis).
Patients with hyperthyroidism or other acute thyroid disorders.
Before and after treatment and scintigraphy with radioactive iodine in patients with thyroid carcinoma.
Dühring’s dermatitis herpetiformis.
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