Description
Irbetan Tablets 300 mg. №20
Ingredients:
Each tablet contains 300 mg of irbesartan.
Mechanism of Action:
Irbesartan works as an angiotensin II receptor antagonist. It selectively blocks the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal glands. By inhibiting the vasoconstrictor and aldosterone-secreting effects of angiotensin II, irbesartan leads to vasodilation and reduced secretion of aldosterone.
Pharmacological Properties:
Irbesartan is a non-peptide compound with a high affinity for the AT1 receptor. It does not exhibit any partial agonist activity at the receptor site. The drug is well-absorbed after oral administration, with peak plasma concentrations reached within 1.5 to 2 hours. Irbesartan is mainly eliminated in the feces and urine as metabolites.
Indications for Use:
Irbetan tablets are indicated for the treatment of hypertension in adult patients. They are effective in reducing blood pressure and decreasing the risk of cardiovascular events, such as strokes, heart attacks, and renal complications.
Contraindications:
Do not use Irbetan tablets if you are pregnant, breastfeeding, have severe liver impairment, or have a history of hypersensitivity to irbesartan or any other component of the product. It is crucial to consult a healthcare provider before initiating treatment with irbesartan.
Side Effects:
Common side effects of irbesartan may include dizziness, fatigue, hypotension, and hyperkalemia. In rare cases, patients may experience angioedema or renal impairment. It is important to report any adverse reactions to a healthcare professional promptly.
Usage Instructions:
The recommended dosage of Irbetan tablets is one 300 mg tablet taken orally once daily. The tablets can be administered with or without food. Patients should adhere to the prescribed dosing regimen to achieve optimal therapeutic outcomes.
Benefits Compared to Analogues:
Irbetan tablets offer advantages over other antihypertensive agents due to their specific mechanism of action and favorable tolerability profile. The efficacy of irbesartan in reducing blood pressure and preventing cardiovascular complications has been well-documented in clinical studies.
Suitable Patient Groups:
Irbetan tablets are suitable for use in adult patients with hypertension. The medication may also be prescribed to elderly individuals as well as specific pediatric populations based on the healthcare provider’s assessment of the patient’s condition.
Storage Conditions and Shelf Life:
Irbetan tablets should be stored at room temperature (20-25°C) in a dry place away from direct sunlight and moisture. The shelf life of the product is typically indicated on the packaging and should be checked before use.
Packaging Description:
Irbetan tablets are typically supplied in blister packs containing 20 tablets each. The packaging should include essential information such as the product name, strength, dosage form, batch number, expiration date, and manufacturer details.
