Description

Irinotecan Medaс for infusions 20 mg/ml. 5 ml. (100 mg.)

Ingredients

Active ingredient: Irinotecan hydrochloride trihydrate. Inactive ingredients may include ethanol, glycocholic acid, and water for injections.

Dosage

Dosage: The recommended dose of Irinotecan Medaс for infusions is determined by the patient’s body surface area and the specific treatment regimen. It is administered intravenously by a healthcare professional.

Indications

Indications: Irinotecan Medaс is indicated for the treatment of colorectal cancer and small cell lung cancer. It is used in combination with other chemotherapy agents.

Contraindications

Contraindications: Irinotecan Medaс is contraindicated in patients with a known hypersensitivity to irinotecan or any of the inactive ingredients. It should not be used in patients with severe bone marrow suppression.

Directions

Administration: Irinotecan Medaс should only be administered by healthcare professionals experienced in the use of chemotherapy agents. It is given as an intravenous infusion over a specific period.

Scientific Evidence

Pharmacological Effects: Irinotecan is a topoisomerase I inhibitor that exerts its antitumor activity by interfering with DNA replication and cell division. It is effective against a variety of solid tumors, including colorectal and lung cancers.

Clinical Trials: Clinical trials have demonstrated the efficacy of Irinotecan in improving overall survival and progression-free survival in patients with advanced colorectal cancer. Studies have also shown its effectiveness in combination therapies for small cell lung cancer.

Additional Information

Safety: Irinotecan Medaс may cause severe diarrhea and myelosuppression. Patients should be closely monitored for these side effects during treatment. It is important to follow the recommended dosage and administration guidelines to minimize the risk of adverse reactions.

Storage: Store Irinotecan Medaс as per the instructions provided in the package insert. Keep it out of reach of children and away from direct sunlight.