Description

Januvia (sitagliptin) Coated Tablets 100 mg. №28

Ingredients:

Each coated tablet contains 100 mg of sitagliptin.

Dosage:

The recommended dose is one 100 mg tablet once daily.

Indications:

Januvia is indicated for the treatment of type 2 diabetes mellitus. It is used to improve glycemic control in adults.

Contraindications:

Do not use Januvia if you have a history of a serious hypersensitivity reaction to sitagliptin. It is not recommended for patients with type 1 diabetes or diabetic ketoacidosis.

Directions:

Take Januvia as directed by your healthcare provider. It can be taken with or without food.

Scientific Evidence:

Studies have shown that sitagliptin, the active ingredient in Januvia, effectively lowers blood sugar levels by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4). This inhibition prolongs the action of incretin hormones, which stimulate insulin release and inhibit glucagon secretion, leading to improved glycemic control.

Additional Information:

It is important to monitor renal function in patients taking Januvia, as it is primarily excreted through the kidneys. Common side effects may include upper respiratory tract infections, headache, and nasopharyngitis.

Januvia (sitagliptin) is a widely prescribed medication for the management of type 2 diabetes. It belongs to a class of drugs known as dipeptidyl peptidase-4 (DPP-4) inhibitors. By targeting the DPP-4 enzyme, Januvia helps increase the levels of incretin hormones in the body, which in turn stimulates the release of insulin and reduces the production of glucose by the liver.

Clinical trials have demonstrated the efficacy of Januvia in improving glycemic control and reducing HbA1c levels in patients with type 2 diabetes. In comparative effectiveness studies, Januvia has shown similar or better outcomes compared to other oral antidiabetic agents. Its convenient once-daily dosing and favorable side effect profile make it a popular choice among healthcare providers and patients.