Description
L-Tiroxine (Levothyroxine Sodium) 75 Tablets 75 mcg. №50
Composition
Active ingredient: Levothyroxine sodium.
Other ingredients: Microcrystalline cellulose, croscarmellose sodium, magnesium stearate, and colloidal silicon dioxide.
Mechanism of Action
Levothyroxine is a synthetic form of thyroxine, a hormone produced by the thyroid gland. It works by increasing thyroid hormone levels in the body, regulating metabolism, energy levels, and growth.
Pharmacological Properties
Levothyroxine acts as a synthetic replacement for thyroxine, effectively treating hypothyroidism and its symptoms by restoring normal thyroid hormone levels in the body.
Indications for Use
L-Tiroxine (Levothyroxine Sodium) 75 mcg tablets are indicated for the treatment of hypothyroidism, including myxedema coma and cretinism.
Contraindications
Contraindications: Untreated thyrotoxicosis, acute myocardial infarction, and hypersensitivity to any component of the product.
Side Effects
Common side effects may include palpitations, tremors, weight loss, and nervousness. Severe allergic reactions are rare but seek immediate medical attention if they occur.
Usage Instructions
Dosage: The usual starting dose is 25-50 mcg per day, with gradual increments of 25 mcg every 2-4 weeks based on clinical response and laboratory parameters.
Directions: Take orally once daily on an empty stomach, 30 minutes to 1 hour before breakfast.
Benefits Compared to Analogues
Levothyroxine has been shown to be superior in improving symptoms and restoring thyroid function compared to other thyroid hormone replacement therapies. It is considered the gold standard in hypothyroidism treatment due to its effectiveness and safety profile.
Suitable Patient Groups
Levothyroxine is suitable for adults and elderly patients with hypothyroidism. Dosage adjustments may be necessary for children under the guidance of a healthcare provider.
Storage Conditions and Shelf Life
Store in a cool, dry place away from light and moisture. Keep out of reach of children. Check the expiration date on the packaging and do not use after the stated shelf life.
Packaging Description
The product is available in a package containing 50 tablets of 75 mcg each. The packaging is designed to protect the tablets from environmental factors and ensure their integrity until use.
Clinical Evidence and Proven Effectiveness
Studies have shown that levothyroxine effectively improves symptoms of hypothyroidism and restores normal thyroid hormone levels. Research published in the Journal of Clinical Endocrinology & Metabolism has demonstrated its efficacy in reducing fatigue, weight gain, and depression in hypothyroid patients.
