Description
Lamictal Tablets 50 mg. №28
Ingredients
Active ingredient: Lamotrigine 50 mg.
Other ingredients: lactose, povidone, maize starch, microcrystalline cellulose, magnesium stearate.
Dosage
Dosage: The usual starting dose of Lamictal for adults and children over 12 years of age is 25 mg every other day for the first two weeks, followed by 25 mg once daily for the next two weeks. The dose is then gradually increased by 25-50 mg every 1-2 weeks.
Indications
Indications: Lamictal is indicated for the treatment of epilepsy in adults and children. It is also used in the management of bipolar disorder to delay mood episodes.
Contraindications
Contraindications: Do not use Lamictal if you are allergic to lamotrigine or any other ingredients in the product. It is contraindicated in patients with a history of Stevens-Johnson syndrome or toxic epidermal necrolysis.
Directions
Directions: Take Lamictal exactly as prescribed by your healthcare provider. Do not alter the dosage or discontinue the medication without consulting your doctor.
Pharmacological Properties
Mechanism of Action: Lamictal works by stabilizing electrical activity in the brain, specifically by blocking sodium channels and modulating glutamate release. This helps in controlling seizures and stabilizing mood in patients with bipolar disorder.
Side Effects
Side Effects: Common side effects of Lamictal may include dizziness, headache, blurred or double vision, nausea, and vomiting. Serious side effects such as skin rash, fever, swollen glands, and unusual bruising or bleeding may occur in rare cases. Contact your healthcare provider immediately if you experience any severe side effects.
Benefits Compared to Analogues
Benefits: Compared to some other antiepileptic drugs, Lamictal has a lower risk of causing weight gain and sedation. It also has a favorable side effect profile in the management of bipolar disorder, making it a preferred choice for many healthcare providers.
Suitable Patient Groups
Suitable Patient Groups: Lamictal can be used in both pediatric and geriatric populations under appropriate medical supervision. It is well-tolerated in children and has been shown to be effective in elderly patients with epilepsy and bipolar disorder.
Storage and Shelf Life
Storage: Store Lamictal tablets in a cool, dry place away from direct sunlight. Keep the medication out of reach of children and pets.
Shelf Life: Check the expiration date on the packaging before use. Do not use Lamictal tablets after the expiration date has passed.
Packaging Description
Lamictal tablets 50 mg. №28 are typically packaged in blister packs to ensure individual tablet protection and ease of use. Each pack contains 28 tablets for a 4-week supply.
Clinical Evidence and Proven Effectiveness
Pharmacological Effects: Lamictal has demonstrated efficacy in reducing seizure frequency in epilepsy and preventing mood episodes in bipolar disorder by stabilizing brain activity through sodium channel blockade and glutamate modulation.
Clinical Trials: Clinical studies have shown that Lamictal is effective in the long-term treatment of bipolar disorder with a favorable side effect profile. Research published in the Journal of Clinical Psychopharmacology supports the use of Lamictal as a reliable option for managing bipolar disorder symptoms.
