Description

Leukeran Coated Tablets 2 mg. №25 Vial

Ingredients:

Each coated tablet contains 2 mg of chlorambucil as the active ingredient.

Dosage:

The dosage of Leukeran should be individualized based on the patient’s condition and response to treatment. It is important to follow the prescribing physician’s instructions carefully.

Indications:

Leukeran is indicated for the treatment of chronic lymphocytic leukemia (CLL), Hodgkin’s disease, and certain types of non-Hodgkin’s lymphomas.

Contraindications:

Leukeran is contraindicated in patients with a history of hypersensitivity to chlorambucil or any of the tablet’s components.

Directions:

The tablets should be taken orally with or without food as directed by the physician. Do not crush or chew the tablets.

Scientific Evidence:

Studies have shown that Leukeran, a nitrogen mustard alkylating agent, exerts its cytotoxic effects by interfering with DNA replication and RNA transcription in rapidly dividing cells. This mechanism of action makes it effective in the treatment of various hematologic malignancies.

Research published in the Journal of Clinical Oncology has demonstrated the efficacy of Leukeran in combination therapy for CLL, leading to improved overall response rates and progression-free survival compared to single-agent therapy.

Additional Information:

• Leukeran should be stored at room temperature away from moisture and heat.
• Pregnant women should avoid handling Leukeran tablets due to the potential risk of harm to the fetus.