Levomecol ointment 40 g. tube

Description

Levomecol Composition
Active ingredients: 1 g of the drug contains: chloramphenicol (in terms of 100% dry matter) 7.5 mg, 6-methyluracil (in terms of 100% dry matter) 40 mg.

Excipients: polyethylene glycol 400, polyethylene glycol 1500.

Levomecol Dosage form
Ointment.

Basic physical and chemical properties: ointment of white or white color with a slightly yellowish tinge, uniform consistency.

Levomecol Pharmacotherapeutic group
Drugs that promote healing (scarring) of wounds.

ATX code D03A X.

Levomecol Pharmacodynamics
Combined preparation for topical use with antimicrobial, reparative and anti-inflammatory effects. Chloramphenicol, which is part of the drug, has an antimicrobial effect, the mechanism of which is associated with a violation of the synthesis of proteins of microorganisms. Acts bacteriostatically, active against gram-positive and gram-negative microorganisms (staphylococcus, streptococcus, Pseudomonas aeruginosa and Escherichia coli). Methyluracil accelerates the processes of cell regeneration, promotes scarring of wounds and has an anti-inflammatory effect.

The polyethylene oxide base adsorbs wound exudate, potentiates the activity of medicinal substances. The drug easily penetrates into tissues without damaging biological membranes, however, the degree of systemic absorption after application of the drug to the skin, wounds and mucous membranes is unknown.

Pharmacokinetics
Has not been studied.

Indications
Treatment of purulent wounds (infected with mixed microbial flora) in the first phase of the wound process, trophic ulcers, bedsores, infected burns, boils, carbuncles.

Contraindications
Hypersensitivity to active ingredients or to other components of the drug.
Psoriasis, eczema, fungal skin lesions.
Interaction with other medicinal products and other types of interactions
Simultaneous use with drugs that inhibit hematopoiesis is undesirable: sulfonamides, cytostatics, pyrazoline derivatives; with biphenyl, barbiturates, ethanol.

The simultaneous use of the drug with erythromycin, oleandromycin, nystatin and levorin increases the antibacterial activity of liniment, and decreases with benzylpenicillin salts.

Application features
The use of antibacterial agents for external use can lead to skin sensitization, which is accompanied by the development of hypersensitivity reactions with the further use of this drug externally or in the form of a dosage form of systemic action.

In the presence of pus or necrotic masses, the antibacterial effect of the drug remains. Do not allow the ointment to come into contact with the mucous membrane of the eyes.

With prolonged (more than 1 month) use of the drug, it is necessary to monitor the state of the peripheral blood picture.

You should not violate the rules for using the drug.