$14.70
Lipodemin 10 is used to treat patients with elevated levels of low-density lipoprotein cholesterol, total cholesterol, apo-lipoprotein B, and triglycerides. Liprimar is used in the treatment of patients in whom diet and exercise did not allow achieving the desired therapeutic effect.
The drug is indicated for the treatment of patients with homozygous hereditary form of hypercholesterolemia. In addition, the drug is prescribed to prevent the development of cardiovascular pathologies in arterial hypertension, smoking, diabetes mellitus and insufficient levels of high-density lipoproteins in the body.
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Description
Lipodemin 10 composition
active substance: atorvastatin;
1 tablet contains atorvastatin calcium equivalent to 10 mg of atorvastatin;
excipients: calcium carbonate; microcrystalline cellulose; lactose monohydrate; croscarmellose sodium; polysorbate 80; hydroxypropylcellulose; magnesium stearate; film coating material (hydroxypropylmethylcellulose, macrogol 8000, titanium dioxide (E 171), talc); simethicone emulsion (simethicone, emulsion-forming stearate, thickener, benzoic acid, sorbic acid).
Dosage form
Film-coated tablets.
Pharmacological properties
Lipodemin 10 is a synthetic hypolipidemic drug. Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonate – the initial and limiting stage of cholesterol biosynthesis.
Lipodemin is a selective competitive inhibitor of HMG-CoA reductase, an enzyme that determines the rate of conversion of 3-hydroxy-3-methylglutaryl coenzyme A to mevalonate, a precursor of sterols, including cholesterol.
Indications
Lipodemin 10 is used to treat patients with elevated levels of low-density lipoprotein cholesterol, total cholesterol, apo-lipoprotein B, and triglycerides. Liprimar is used in the treatment of patients in whom diet and exercise did not allow achieving the desired therapeutic effect.
The drug is indicated for the treatment of patients with homozygous hereditary form of hypercholesterolemia. In addition, the drug is prescribed to prevent the development of cardiovascular pathologies in arterial hypertension, smoking, diabetes mellitus and insufficient levels of high-density lipoproteins in the body.
Contraindications
Lipodemin 10 is not prescribed to patients who have been found to be intolerant to the drug, as well as to those who suffer from liver diseases, accompanied by increased activity of hepatic transaminases of unknown etiology.
With extreme caution, the drug is prescribed to patients with alcoholism, as well as to those who suffer from any liver diseases.
Children
The drug cannot be administered to children under 10 years of age.
Application during pregnancy and lactation
The drug is not used to treat nursing. During the feeding period, the administration of the drug is possible only after the cessation of lactation.
Method of administration and dosage
Lipodemin 10 is taken orally, regardless of food intake. At the beginning of drug therapy, it is necessary to achieve control over hypercholesterols with the help of diet, active exercise and weight loss in obese patients, as well as correct treatment of the underlying disease.
With Lipodemin therapy, the patient is recommended a usual cholesterol-lowering diet, which he must follow throughout the entire period of treatment. When the drug is prescribed, its amount can vary from 10 to 20 mg per day. The choice of the required dose of the agent takes into account the initial LDL-C. The maximum daily dose should not exceed 80 mg. In the course of treatment, the dose is adjusted every two 2 or 4 weeks while monitoring the level of lipids in the blood plasma.
Overdose
When taking large doses of the drug, the therapeutic effect does not increase, but the risk of side effects increases. In case of an overdose of the drug, gastric lavage, the appointment of enterosorbents, drinking plenty of fluids and taking laxatives are recommended.
Side effects
When the correct dose of the drug is taken, drug treatment is very rarely accompanied by the development of side effects. However, in some cases, the patient may experience paresthesias, headaches, neuropathy, flatulence, abdominal pain, nausea, pancreatitis, muscle cramps, myalgia, myositis, allergic reactions, impaired erectile function, memory impairment, dizziness, increased fatigue, peripheral edema and hemorrhagic strokes.
Storage conditions and periods
Store in a dark, dry place. The shelf life of the drug is 3 years.
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