Lira tablets (citicoline) coated tablets 500 mg. №30

Description

Lira tablets composition
active substance: citicoline;
1 tablet contains citicoline sodium 522.5 mg in terms of 100% dry matter (equivalent to citicoline 500.0 mg);
excipients: microcrystalline cellulose, anhydrous colloidal silicon dioxide, croscarmellose sodium, hydrogenated castor oil, talc, magnesium stearate;
film casing: Opadry white 03 F 180011 (hydroxypropyl methylcellulose, titanium dioxide E 171, macrogol 8000); Opadry white II 85 F 18422 (polyvinyl alcohol, titanium dioxide E 171, macrogol 4000, talc).

Dosage form
Film-coated tablets.

Pharmacological properties
Citicoline preserves neuronal energy stores, inhibits apoptosis, which improves cholinergic transmission.
Clinical studies have shown that citicoline significantly increases the indicators of functional recovery in patients with acute cerebrovascular accident, which coincides with a slowdown in the growth of ischemic brain damage according to neuroimaging data. In patients with traumatic brain injury, citicoline accelerates recovery and reduces the duration and intensity of post-traumatic stress disorder.
Citicoline improves the level of attention and consciousness, helps to reduce the manifestations of amnesia, cognitive and other neurological disorders associated with cerebral ischemia.

Indications:

• Stroke, acute phase of cerebrovascular accidents, treatment of complications and consequences of cerebrovascular accidents.
• Traumatic brain injury and its neurological consequences.
• Cognitive and behavioral disorders due to chronic vascular and degenerative brain disorders.

Contraindications
Hypersensitivity to any component of the drug.
Increased tone of the parasympathetic nervous system.

Children
The experience of using the drug in children is limited.

Application during pregnancy or lactation
There is insufficient data on the use of Lyra in pregnant women.
There are no data on the excretion of citicoline in breast milk and its effect on the fetus. During pregnancy and lactation, the drug is prescribed only when the expected benefit to the mother outweighs the potential risk to the fetus.

Method of administration and dosage
Take Lira tablets by mouth with plenty of water. The recommended dose for adults is 500 mg to 2000 mg per day (1 to 4 tablets).
Doses of the drug and the duration of treatment depend on the severity of the brain damage and are set by the doctor.
Elderly patients do not require dose adjustment.

Side effects:

• From the central and peripheral nervous system: severe headache, vertigo, hallucinations.
• From the side of the cardiovascular system: arterial hypertension, arterial hypotension, tachycardia.
• From the respiratory system: shortness of breath.
• From the digestive system: nausea, vomiting, diarrhea.
• From the immune system: allergic reactions, including: rash, hyperemia, exanthema, urticaria, purpura, pruritus, angioedema, anaphylactic shock.
• General reactions: chills.

Shelf life
2 years.
Do not use the drug after the expiry date indicated on the package.

Storage conditions
Store Lira tablets in their original packaging at a temperature not exceeding 25 ºС.
Keep out of the reach of children.