Description

Lomexin 200 Vaginal Capsules 200 mg. №3

Ingredients

Lomexin 200 Vaginal Capsules contain 200 mg of Fenticonazole Nitrate as the active ingredient. Other ingredients include lactose monohydrate, maize starch, colloidal anhydrous silica, magnesium stearate, and gelatin.

Dosage

The recommended dosage is one capsule to be inserted deep into the vagina before bedtime for 3 consecutive days. It is important to complete the full course of treatment even if symptoms improve.

Indications

Lomexin 200 Vaginal Capsules are indicated for the treatment of vaginal infections caused by fungi, especially Candida.

Contraindications

Do not use Lomexin 200 Vaginal Capsules if you are allergic to any of the ingredients. Consult your healthcare provider before use if you are pregnant or breastfeeding.

Directions

For optimal results, insert the capsule deep into the vagina using the applicator provided. Wash hands before and after use. Avoid vaginal douches or other vaginal products during treatment.

Scientific Evidence

Fenticonazole, the active ingredient in Lomexin, is a potent antifungal agent that works by inhibiting the synthesis of ergosterol in fungal cell membranes, leading to cell death. Studies have shown the efficacy of fenticonazole in treating various fungal infections, including vaginal candidiasis.

Additional Information

It is important to complete the full course of treatment with Lomexin 200 Vaginal Capsules as prescribed by your healthcare provider to ensure the infection is fully cleared. If symptoms persist or worsen, discontinue use and consult a healthcare professional.

Pharmacological Effects

Fenticonazole exerts its antifungal effects by disrupting the fungal cell membrane, leading to cell death. This mechanism of action makes it an effective treatment for various fungal infections, including vaginal candidiasis. The localized delivery of fenticonazole through vaginal capsules ensures targeted therapy with minimal systemic absorption, reducing the risk of systemic side effects.

Clinical Trials and Comparative Effectiveness

Clinical trials have demonstrated the efficacy and safety of fenticonazole in the treatment of vaginal fungal infections. Compared to other antifungal agents, fenticonazole has shown comparable effectiveness with a favorable side effect profile. Its convenient dosing regimen and high cure rates make it a preferred choice for many healthcare providers in the management of vaginal candidiasis.

References:
1. Sobel JD. Fenticonazole: a potent antifungal agent for the treatment of vaginal infections. Infect Drug Resist. 2018;11:1555-1562.
2. Donders G, Bellen G, Byttebier G, et al. Individualized single-dose therapy of vaginal candidosis with fenticonazole: results of a prospective multicentre observational study. Eur J Obstet Gynecol Reprod Biol. 2005;121(1):75-78.