$5.10
This drug Lopedium is used to treat diarrhea, regardless of its cause, that is, any etiology.
It is effective for diarrhea, accompanied by the absence of gas discharge from the intestines, and, as a result, abdominal discomfort, spastic pain and flatulence.
It is also prescribed for the treatment of acute attacks of diarrhea caused by irritable bowel syndrome.
Description
Lopedium composition
active substance: loperamide hydrochloride;
1 capsule contains loperamide hydrochloride 2 mg;
excipients: lactose monohydrate, corn starch, talc, magnesium stearate; capsule shell: gelatin, titanium dioxide (E 171), iron oxide black (E 172), iron oxide yellow (E 172), patented blue V (E 131).
Dosage form
Hard capsules.
Pharmacological properties
This drug Lopedium belongs to the group of antidiarrheal drugs that inhibit intestinal peristalsis.
The active component of this drug, loperamide hydrochloride, is able to bind to receptors in the intestinal walls, as a result of which its peristalsis is inhibited.
The action of the drug entails an increase in the transit time of the intestine, due to which the resorption of water and ionic solutions, which are responsible for the transmission of impulses – electrolytes, increases.
Loperamide does not have a central effect on the body. Does not lead to changes in the physiological microflora in the intestine or an increase in the tone of the anus sphincter. As a result, the urge to defecate decreases, the risk of fecal incontinence.
Indications
This drug Lopedium is used to treat diarrhea, regardless of its cause, that is, any etiology.
It is effective for diarrhea, accompanied by the absence of gas discharge from the intestines, and, as a result, abdominal discomfort, spastic pain and flatulence.
It is also prescribed for the treatment of acute attacks of diarrhea caused by irritable bowel syndrome.
Contraindications
Do not apply if the patient has hypersensitivity (allergy).
The drug should be administered with caution to patients with severely impaired liver function, since their first pass metabolism is slowed down.
This drug should not be used as monotherapy for acute dysentery, which is characterized by bloody stools and high fever.
The use of this drug is contraindicated in patients with acute ulcerative colitis or pseudomembranous colitis if they are caused by treatment with broad-spectrum antibiotics.
Not suitable for patients with bacterial enterocolitis due to Salmonella, Shigella or Campylobacter.
Children
It is not used in pediatrics until the age of 12.
Application during pregnancy and lactation
For the treatment of pregnant women, it can be used with great caution, in urgent need.
If there is a need to take this drug, then lactation (breastfeeding) should be suspended during treatment.
Method of administration and dosage
Adults and children over 12 years of age take an initial dosage of 2 capsules. Then, after each bowel movement, with liquid contents, another 1 capsule is taken.
Drink the capsule with a sufficient amount of water.
The maximum number of tablets you can take per day is 6 capsules.
The duration of such treatment cannot exceed 2 days if there is no noticeable effect from the application.
When treating patients with impaired renal function, it is not necessary to reduce the dose of the drug.
Overdose
In case of an overdose, theoretically side effects can be observed in the form of depression of the central nervous system in the form of stupor, impaired coordination, drowsiness, miosis, muscle hypertonia, paralytic intestinal obstruction.
In case of an overdose of more than 40 mg per day, arrhythmia, syncope, heart rhythm disturbances, up to cardiac arrest may occur.
Naloxone is taken as an antidote. It is necessary to monitor the patient’s condition within 48 hours.
Side effects
Therapy with this drug rarely causes adverse reactions, even with prolonged use. In rare cases, the following were observed:
- rash, bullous rash, pruritus, allergic urticaria, anaphylactic shock;
- toxic epidermal necrolysis;
- constipation, bloating, flatulence;
- dry mouth, urinary retention;
- stupor, miosis, increased fatigue.
If constipation occurs, the drug should be stopped immediately.
Storage conditions and periods
The shelf life of the drug is no more than 3 years from the production date indicated on the package.
Store Lopedium in a dry place out of the reach of children, at a temperature not exceeding 25 ° C.
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