Description

Lopirel 75 Coated Tablets 75 mg. №30

Ingredients:

Each coated tablet contains 75 mg of clopidogrel bisulfate.

Dosage:

The usual dose is one tablet daily, taken orally with or without food, or as directed by a healthcare professional.

Indications:

Lopirel 75 is indicated for the prevention of blood clots in patients with a history of recent heart attack or stroke, or peripheral arterial disease.

Contraindications:

Do not use Lopirel 75 if you are allergic to clopidogrel or have active bleeding such as a stomach ulcer or bleeding in the brain.

Directions:

Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence:

Clopidogrel, the active ingredient in Lopirel 75, is a platelet aggregation inhibitor that works by irreversibly binding to the P2Y12 ADP receptor on platelets, preventing platelet activation and aggregation. This mechanism of action has been extensively studied and proven effective in reducing the risk of cardiovascular events in patients with atherosclerosis.

Additional Information:

It is essential to inform your healthcare provider about all medications, including over-the-counter drugs and supplements, before starting Lopirel 75 to prevent potential drug interactions. Common side effects may include bruising, bleeding, and gastrointestinal upset. If you experience any unusual bleeding or bruising, contact your doctor immediately.

Several clinical trials have demonstrated the efficacy of clopidogrel in reducing the risk of recurrent cardiovascular events. The CAPRIE study showed that clopidogrel was superior to aspirin in reducing the combined risk of ischemic stroke, myocardial infarction, or vascular death in patients with atherosclerotic vascular disease.