Loprax powder for suspension 100 mg/5 ml. 50 ml. №1

Description

Loprax  composition
active ingredient: cefixim;
5 ml of the suspension contain: cefixim trihydrate in an amount corresponding to cefixim 100 mg;
auxiliary substances: sucrose, xanthan gum, sodium benzoate (E 211), orange flavoring.

Dosage form
Powder for oral suspension.

Pharmacological properties
This is a 3rd generation antibiotic cephalosporin. Its bactericidal activity (the ability to kill bacteria) is due to the inhibition of the production of components of cell membranes. Active against most Gram (+) and Gram (-) microorganisms. This drug is characterized by high resistance to penicillinases, cephalosporinases (β-lactamases) of bacteria. Активен против следующих микроорганизмов: Streptococcus pneumonіae, Streptococcus pyogenes, Haemophіlus influenzae, Moraxella catarrhalіs, Escherichia coli, Proteus mirabіlis, Neisserіa gonorrhoeae, Streptococcus agalactiae, Haemophilus paraіnfluenzae, Proteus vulgarіs, Klebsiella pneumonіae, Klebsіella oxytoca, Pasteurella multocіda, Providencіa spp., Salmonella spp., Shіgella spp., Citrobacter amalonatіcus, Citrobacter dіversus. Enterococcus spp., Listeria monocytogenes, Pseudomonas spp., most strains of Enterobacter spp., Staphylococcus spp., Bacteroides fragilis, Clostridium spp.

Indications
Loprax is prescribed for infections caused by microorganisms sensitive to it:

• in streptococcal tonsillitis, pharyngitis;
• for sinusitis;
• acute bronchitis;
• in acute middle otitis;
• with uncomplicated gonorrhea;
• in exacerbation of chronic bronchitis;
• in uncomplicated urinary tract infections;
• in shigellosis.

Contraindications
Loprax cannot be used:

• in allergies to cephalosporins, penicillins;
• cefixim allergy, intolerance of auxiliary components;
• y children up to 6 months;
• in porphyria.

With caution, Loprax is used for kidney failure, colitis (in the past), in the elderly, pregnant women.

Children
This drug is used in pediatric practice for children from 6 months.

Use in pregnancy and breastfeeding
Use is allowed only when prescribed by a doctor, when the intended benefit to the mother exceeds the risk to the fetus. If it is necessary to use during lactation, feeding should be stopped.

Method of use and doses
Loprax is used inside.
Before cooking, you need to turn over and shake the bottle, add boiled cold water to the mark, in 2 takes, each time shaking the bottle until the suspension is homogeneous.
The suspension may be taken 5 minutes after preparation.
The medicine is taken regardless of food intake.

• Dosing for adults, children weighing more than 50 kg – 400 mg/day in one or two doses.
• Dosing for children weighing 25-50 kg – 8 mg/day in one take.

The duration of treatment depends on the course of the disease, the type of infection. After the disappearance of the symptoms of infection, it is advisable to continue taking the medicine for at least 2-3 days.

Overdose
When taken at a dose exceeding the maximum daily dose, side effects can be increased.
Overdose treatment: gastric washing, symptomatic, supportive therapy.

Side effects:

• Blood test changes: leukopenia, thrombocytopenia, agranulocytosis, pancytopenia, eosinophilia, blood clotting disorder.
• Urogenital disorders: increased concentration of creatinine in the blood, hematuria.
• Allergic reactions: urticaria, cutaneous itching, Lyell syndrome, drug fever, hemolytic anemia, interstitial nephritis, syndrome resembling serum disease, anaphylactic shock.
• Digestive disorders: abdominal pain, diarrhea, digestive disorders, nausea, pseudomembranous colitis.
• Neurological disorders: headaches, dizziness, dysphoria.
• Hepatobiliary disorders: increased levels of alkaline phosphatase, transaminase, hepatitis, cholestatic jaundice.

Terms and conditions of storage
Store Loprax at 15-25 ° C for no more than 3 years. Store the finished suspension for no more than 14 days (in the refrigerator).