Description

Lorista H Coated Tablets 50 mg/12.5 mg. №60

Ingredients

Lorista H tablets contain 50 mg of losartan potassium and 12.5 mg of hydrochlorothiazide as active ingredients. The tablets also include inactive ingredients such as lactose, microcrystalline cellulose, and magnesium stearate.

Dosage

The recommended dosage of Lorista H is one tablet once daily. It is important to follow the instructions provided by your healthcare provider for the correct dosage and duration of treatment.

Indications

Lorista H tablets are indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled by either losartan or hydrochlorothiazide alone.

Contraindications

Do not take Lorista H tablets if you are allergic to any of the ingredients, if you are pregnant, or if you have severe renal impairment. It is important to consult with your doctor before starting this medication.

Directions

Take Lorista H tablets orally with or without food as directed by your healthcare provider. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.

Scientific Evidence

Studies have shown that the combination of losartan and hydrochlorothiazide in Lorista H tablets is effective in lowering blood pressure in patients with hypertension. Research published in the Journal of Clinical Hypertension demonstrated that the dual therapy provided better blood pressure control compared to monotherapy with either losartan or hydrochlorothiazide alone.

Additional Information

It is important to regularly monitor your blood pressure while taking Lorista H tablets and report any significant changes to your healthcare provider. Avoid consuming alcohol while on this medication as it may increase the risk of side effects. If you experience any severe side effects such as dizziness or difficulty breathing, seek immediate medical attention.

Pharmacological Effects: Losartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict, while hydrochlorothiazide helps the kidneys remove excess salt and water from the body, leading to decreased blood volume and lower blood pressure.

Clinical Trials: Clinical trials have demonstrated the efficacy and safety of Lorista H in the management of hypertension. A study published in the American Journal of Hypertension showed that the combination therapy was well-tolerated and effective in reducing both systolic and diastolic blood pressure levels.