Description

Lospirin (Acetylsalicylic Acid) Tablets 75 mg. №120

Ingredients

Active ingredient: Each tablet contains 75 mg of acetylsalicylic acid.

Dosage

Recommended dosage: Take **one tablet** orally once a day with a full glass of water, or as directed by a healthcare professional.

Indications

Indicated for: Relief of mild to moderate pain, fever, inflammation, and prevention of cardiovascular events.

Contraindications

Do not use if: Allergic to acetylsalicylic acid, have a history of gastrointestinal bleeding, or are under 18 years old without medical supervision.

Directions

Directions for use: Swallow the tablet whole with water. Do not crush or chew. Follow the dosage instructions provided.

Scientific Evidence

Acetylsalicylic acid, the active ingredient in Lospirin tablets, has been extensively studied for its **anti-inflammatory**, **analgesic**, and **antiplatelet** effects. Research has shown that acetylsalicylic acid inhibits the enzyme cyclooxygenase, thereby reducing the production of prostaglandins involved in pain, inflammation, and fever. Additionally, its antiplatelet properties help prevent blood clot formation, reducing the risk of cardiovascular events.

Additional Information

It is important to note that **long-term use** of acetylsalicylic acid may increase the risk of gastrointestinal bleeding and ulcers. Patients with a history of such conditions should consult their healthcare provider before using Lospirin tablets. **Avoid** taking other NSAIDs or blood thinners concurrently without medical advice.

Pharmacological Effects and Clinical Trials

Acetylsalicylic acid exerts its pharmacological effects by irreversibly inhibiting the enzyme cyclooxygenase, thereby reducing the production of prostaglandins. This mechanism not only provides pain relief and reduces inflammation but also plays a crucial role in its cardioprotective effects by inhibiting platelet aggregation.

Clinical trials have demonstrated the efficacy of acetylsalicylic acid in reducing the risk of cardiovascular events such as heart attacks and strokes. The landmark study by the Antithrombotic Trialists’ Collaboration showed a significant reduction in the incidence of major cardiovascular events with the use of low-dose aspirin, highlighting the importance of acetylsalicylic acid in preventive cardiology.

Overall, Lospirin tablets containing acetylsalicylic acid offer a well-established therapeutic option for pain relief, fever reduction, inflammation management, and cardiovascular event prevention, supported by robust scientific evidence and clinical trials.