Description

Lozap 100 Plus Coated Tablets 100 mg/25 mg. №90

Ingredients:

Each coated tablet contains 100 mg of losartan potassium and 25 mg of hydrochlorothiazide.

Dosage:

The recommended dosage is one tablet daily, or as prescribed by a healthcare professional.

Indications:

Lozap 100 Plus is indicated for the treatment of hypertension in patients whose blood pressure is not adequately controlled by losartan or hydrochlorothiazide alone.

Contraindications:

Do not use Lozap 100 Plus if you are allergic to any of the ingredients, pregnant, or have severe renal impairment.

Directions:

Swallow the tablet whole with a glass of water. It can be taken with or without food.

Scientific Evidence:

Studies have shown that the combination of losartan and hydrochlorothiazide in Lozap 100 Plus provides a synergistic effect in lowering blood pressure. Research published in the Journal of Clinical Hypertension demonstrated that this combination therapy was more effective than monotherapy in reducing both systolic and diastolic blood pressure levels.

Additional Information:

It is important to monitor electrolyte levels and renal function regularly while taking Lozap 100 Plus, as hydrochlorothiazide can cause electrolyte imbalances. This medication may also interact with other drugs, so consult your healthcare provider before starting Lozap 100 Plus.

Pharmacological Effects:

Losartan works by blocking the action of angiotensin II, a substance in the body that causes blood vessels to constrict. This results in blood vessels dilating, which lowers blood pressure. Hydrochlorothiazide, on the other hand, is a diuretic that helps the body eliminate excess salt and water, further reducing blood volume and blood pressure.

Clinical Trials and Comparative Effectiveness:

In a comparative study published in the American Journal of Hypertension, Lozap 100 Plus was found to be more effective in lowering blood pressure compared to other combination therapies. The study also reported a lower incidence of side effects with Lozap 100 Plus, making it a favorable choice for hypertensive patients.