Magnemax (magnesium, pyridoxine) coated tablets №30

Description

Magnemax composition
active substances: magnesium, pyridoxine;
1 tablet contains magnesium citrate anhydrous 618.43 mg in terms of magnesium 100 mg, pyridoxine hydrochloride 10 mg;
excipients: lactose monohydrate; polyethylene glycol 6000; magnesium stearate; talc; dry mixture “Opadry white” containing titanium dioxide (E 171), hypromellose, triacetin (E 1518).

Dosage form
Film-coated tablets.

Pharmacological properties
This is a combined preparation of vitamin B6 and magnesium.
Vitamin B6 is involved in the synthesis of the hormone serotonin, is involved in protein synthesis, incl. enzymes, histamine, hemoglobin, GABA, glutamic acid, lowers blood cholesterol levels, improves the contractility of the heart muscles, promotes the conversion of folic acid into the active form. Participates in the production of neurotransmitters, is necessary for the normal functioning of the nervous system, liver, takes part in the formation of erythrocytes, promotes the absorption of proteins, fats, has a lipotropic effect. Reduces spasms, muscle cramps, numbness of the limbs, acts as a diuretic.
Magnesium affects almost all bodily functions. It is one of the main elements in energy processes, it is necessary for the formation of bones and teeth, regulates the permeability of cell membranes and their organelles, participates in the functioning of more than 300 enzymes, protects cells from excessive calcium intake, is a calcium antagonist, increases the activity of the antioxidant defense system, reduces convulsive readiness of the body (with eclampsia, preeclampsia), has antithrombotic activity. With magnesium deficiency, neurological disorders (decreased concentration, tremors, muscle spasms) can be observed.

Indications
Magnemax is used to treat / prevent magnesium deficiency, which can manifest itself as increased excitability, irritability, anxiety, transient weakness, sleep disturbances, anxiety, muscle cramps, and a tingling sensation in the muscles.

Contraindications:

• with intolerance to the components of the drug;
• with the simultaneous use of other medicines containing magnesium;
• with the simultaneous use of levodopa;
• with hypermagnesemia (increased concentration of magnesium in the blood);
• with hypervitaminosis B6;
• with severe renal failure;
• with atrioventricular block;
• with myasthenia gravis;
• with severe arterial hypotension;
• with diarrhea;
• with phenylketonuria.

Children
This drug is used in pediatric practice for children from 6 years old.

Application during pregnancy and lactation
During pregnancy and lactation, the usual daily dose for adults is used.

Method of administration and dosage
Magnemax is used orally during meals.

• The standard dose for adults is 3-4 tablets per day, divided into 2-3 doses.
• The standard dose for children over 6 years old is 2-4 tablets per day, divided into 2-3 doses.

The use is discontinued as soon as the level of magnesium in the blood reaches normal.
The duration of treatment is determined individually.

Overdose
Symptoms: renal failure, weakness, vomiting, decreased blood pressure, bradycardia, ECG changes, slow reflexes, paresthesia, hyporeflexia, confusion, coma, respiratory failure, cardiac arrest, respiratory paralysis, anuria (less than 50 ml of urine per day) …
As an antidote, you can use calcium preparations at a dose of 100-200 mg for
5-10 minutes, forced diuresis, dialysis.

Side effects
Possible manifestations of hypersensitivity (including anaphylaxis, allergic dermatitis, rash, itching, urticaria, Quincke’s edema), digestive disorders.

Storage conditions and periods
Store Magnemax for no more than two years at temperatures up to +25 ° C.
It is forbidden to use after the expiry date indicated on the package.
Parents are obliged to ensure the safety of children, excluding the possibility of their access to medicine.