Medrolgyn (ketorolac) eye drops 5 mg/ml. 5 ml. vial

Description

Medrolgyn composition
active substance: ketorolac;
1 ml of solution contains ketorolac tromethamine 5 mg;
Excipients: octoxynol 40, disodium edetate, sodium chloride, benzalkonium chloride, sodium hydroxide or hydrochloric acid, purified water.

Dosage form
Eye drops, solution.

Pharmacological properties
The drug in question Medrolgyn belongs to the group of non-steroidal anti-inflammatory drugs used in ophthalmic practice.
The main active ingredient is ketorolac in the form of tromethamine.
It has an analgesic, anti-inflammatory, antipyretic effect.
The drug owes its action to the fact that it has the property of inhibiting the biosynthesis of prostaglandins – lipid mediator substances with physiological activity, derivatives of prostanoic acid.
By themselves, prostaglandins are not pain mediators, and do not cause inflammation. At the same time, these substances provide sensitization of the responsible receptors with respect to pain mediators (histamine and bradykinin).
As a non-steroidal anti-inflammatory agent, ketorolac has the ability to block cyclooxygenase, reducing the production of prostaglandins, which blocks the development of inflammatory processes, as well as reducing the sensation of pain.

Indications
Medrolgyn is used to treat pain and inflammation of non-infectious origin, including after cataract surgery.

Contraindications
The drug in question is contraindicated for use in cases where the patient has severe hypersensitivity (allergy) to the main or one of the auxiliary components, NSAIDs.
It should be borne in mind that non-steroidal anti-inflammatory drugs slow down the healing of wounds and injuries, lengthen the period of bleeding.
It should be used with caution in patients diagnosed with:

• keratitis;
• energy of the cornea;
• diabetes mellitus;
• dry eye syndrome;
• rheumatoid arthritis.

Children
Not applicable for the treatment of children under 12 years of age

Application during pregnancy and lactation
This drug is contraindicated in the treatment of pregnant women. It is permissible to use only if the expected benefit to the mother outweighs the potential risk to the fetus.
If it is necessary to administer the drug during breastfeeding, then during treatment, lactation should be suspended.

Method of administration and dosage
This Medrolgyn preparation is used by instilling 1 drop into each affected eye, 2 times a day – in the morning and in the evening, preferably at regular intervals.
Instillation begins 1 day before the operation to remove the cataract, to prevent the development of the inflammatory process.
The instillation is continued for the next 2 weeks following the operations.
It is also permissible to use this drug on the day of surgery.
When instilling, do not allow the tip of the bottle to touch the cornea of ​​the eye. After use, the disposable bottle should be discarded and not reused.

Overdose
Overdose if the instructions for use are followed, overdose is unlikely.
In case of accidental ingestion, an increased fluid intake is recommended to dilute the ingested drug.

Side effects
In some cases, there may be some side effects in the form of:

• increased intraocular pressure (glaucoma);
• hyperemia of the conjunctiva of the eye;
• hemorrhage in the cornea of ​​the eye;
• corneal edema;
• pain and pain in the eyes;
• headache;
• lacrimation;
• blurred vision (short-term).

If there are side effects not described in the instructions, you should inform your doctor to adjust the prescribed treatment.

Storage conditions and periods
The shelf life is up to 2 years.
Storage temperature – no higher than 25 ° С.