Description

Metamin (metformin hydrochloride) Coated Tablets 1000 mg. №30

Ingredients

Each coated tablet contains 1000 mg of metformin hydrochloride.

Dosage

The usual dose is one tablet taken orally with meals.

Indications

Metamin is indicated for the treatment of type 2 diabetes mellitus.

Contraindications

Do not use Metamin in patients with renal impairment, severe infection, or dehydration.

Directions

Follow the instructions provided by your healthcare provider for the best results.

Scientific Evidence

Metformin, the active ingredient in Metamin, is a first-line medication for the management of type 2 diabetes. It works by decreasing glucose production in the liver and improving insulin sensitivity in the body’s tissues. Several studies have shown the effectiveness of metformin in lowering blood sugar levels and reducing the risk of diabetes-related complications.

Additional Information

It is important to monitor your blood sugar levels regularly while taking Metamin to ensure optimal control of your diabetes. In case of any unusual symptoms or side effects, consult your healthcare provider immediately. Store the tablets in a cool, dry place away from direct sunlight.

Pharmacological Effects

Metformin hydrochloride, the main component of Metamin tablets, primarily acts by suppressing glucose production in the liver and increasing insulin sensitivity in peripheral tissues. This dual mechanism helps to lower blood glucose levels and improve the body’s response to insulin. Additionally, metformin has been associated with weight loss and cardiovascular benefits in diabetic patients.

Clinical Trials and Comparative Effectiveness

Several clinical trials have demonstrated the efficacy of metformin in reducing hemoglobin A1c levels and improving glycemic control in patients with type 2 diabetes. Compared to other oral antidiabetic agents, metformin has shown comparable or even superior effectiveness in managing blood sugar levels with a lower risk of hypoglycemia. Its favorable safety profile and cost-effectiveness make it a preferred choice in diabetes management.