Description
Metotab (Methotrexate) Tablets 10 mg. №30
Ingredients:
Each tablet contains 10 mg of Methotrexate.
Dosage:
The usual adult dosage is 7.5 to 20 mg once weekly. Dosage may vary based on the condition being treated.
Indications:
- Metotab tablets are indicated for the treatment of certain types of cancer, severe psoriasis, and rheumatoid arthritis.
- It works by slowing or stopping the growth of cancer cells and suppressing the immune system.
Contraindications:
- Do not take Metotab if you are pregnant, breastfeeding, or have liver disease.
- Discuss your medical history with a healthcare provider before starting this medication.
Directions:
Take Metotab tablets orally as directed by your doctor. It is usually taken once a week. Follow all instructions on the product package.
Scientific Evidence:
Methotrexate has been studied for its efficacy in treating various conditions. Research has shown its effectiveness in certain types of cancer and autoimmune diseases like rheumatoid arthritis.
Additional Information:
- Regular blood tests are important to monitor your body’s response to the medication.
- Inform your doctor of any side effects or concerns.
- Avoid prolonged sun exposure while on Methotrexate therapy.
Pharmacological Effects:
Methotrexate inhibits dihydrofolate reductase, suppressing cell proliferation and modulating the immune response. This mechanism makes it effective in treating cancer and autoimmune diseases.
Clinical Trials and Comparative Effectiveness:
Clinical trials have shown Methotrexate’s efficacy in comparison to other DMARDs for rheumatoid arthritis. It is more effective in achieving disease remission and improving physical function, slowing disease progression, and enhancing quality of life in patients.
