Description

Metotab (methotrexate) tablets 2.5 mg. №100

Ingredients

Active ingredient: Methotrexate 2.5 mg per tablet.

Dosage

Dosage: The usual adult dosage of Metotab is 7.5 mg once weekly, taken as a single dose or divided into 2.5 mg every 12 hours for 3 doses. Dosage may vary based on the condition being treated. Consult a healthcare professional for personalized dosing instructions.

Indications

Indications: Metotab is indicated for the treatment of various conditions including rheumatoid arthritis, psoriasis, and certain types of cancer such as leukemia and lymphoma.

Contraindications

Contraindications: Do not use Metotab if you are pregnant, breastfeeding, have liver disease, or a history of alcohol abuse. It is important to discuss your medical history with a healthcare provider before starting this medication.

Directions

Directions: Take Metotab exactly as prescribed by your healthcare provider. Swallow the tablet whole with a full glass of water. Do not crush or chew the tablet.

Scientific Evidence

Metotab (methotrexate) has been extensively studied for its efficacy in treating various autoimmune diseases and cancers. Research has shown that methotrexate works by inhibiting dihydrofolate reductase, an enzyme involved in the synthesis of DNA, RNA, and proteins. This action helps to suppress the overactive immune system in conditions like rheumatoid arthritis and psoriasis.

Studies have demonstrated the effectiveness of methotrexate in reducing disease activity and improving symptoms in patients with rheumatoid arthritis. Additionally, clinical trials have shown that methotrexate can induce and maintain remission in certain types of leukemia and lymphoma.

Additional Information

It is important to have regular monitoring of blood counts and liver function tests while taking Metotab to prevent potential side effects. Common side effects may include nausea, vomiting, and liver toxicity. Consult your healthcare provider if you experience any adverse reactions.

Before starting Metotab, inform your healthcare provider about all the medications you are taking, including prescription, over-the-counter, and herbal supplements, to avoid potential drug interactions.