Mexicor solution for injections 50 mg/ml. 2 ml. ampoules №10

Description

Mexicor composition
active substance: ethylmethylhydroxypyridine succinate;
1 ml of solution contains ethylmethylhydroxypyridine succinate – 50 mg;
Excipients: succinic acid, edetate disodium, water for injections.

Dosage form
Solution for injection.

Pharmacological properties
It is a remedy that improves metabolic processes. It is a membrane protector, an inhibitor of free radical processes. Has a stress-protective, nootropic, antihypoxic, anxiolytic and anticonvulsant effect. Increases tissue resistance to oxygen-dependent pathological conditions (hypoxia, shock, ischemia, alcohol intoxication, cerebral circulation disorders).

Indications
Mexicor is used:

• with acute / chronic disorders of cerebral circulation (traumatic brain injury and its consequences, discirculatory encephalopathy, neurocirculatory dystonia, moderate cognitive disorders of atherosclerotic genesis);
• with anxiety disorders;
• with neuroses, neurosis-like states;
• with acute myocardial infarction;
• with withdrawal symptoms in alcoholics with a predominance of neurosis-like, neurocirculatory disorders;
• with acute intoxication with antipsychotic drugs;
• with primary open-angle glaucoma;
• with acute intra-abdominal purulent-inflammatory processes (peritonitis, acute necrotizing pancreatitis).

Contraindications:

• with intolerance to the components of the drug;
• with severe dysfunction of the liver, kidneys.

Application during pregnancy and lactation
Not applicable.

Method of administration and dosage
Mexicor is used intramuscularly or intravenously (drip, jet). Introduce the solution slowly (within 5-7 minutes, drip – 40-60 drops / minute).
The initial dose for adults is 50-100 mg 1-3 times / day, gradually increasing until a therapeutic effect is obtained. The maximum is 800 mg / day.

• In acute disorders of cerebral circulation – 200-300 mg intravenously once a day in the first 2-4 days, then – 100 mg intramuscularly 3 times / day. The duration of therapy is 10-14 days.
• With TBI – 200-500 mg 2-4 times / day for 10-15 days.
• With discirculatory encephalopathy – 100 mg intravenously 2-3 times / day for 14 days, then – 100 mg / day intramuscularly for the next two weeks.
• With mild cognitive impairment, anxiety – 100-300 mg / day for 14-30 days.
• With open-angle glaucoma – 100-300 mg / day intramuscularly for 14 days.
• With withdrawal symptoms – 100-200 mg intramuscularly 2-3 times / day for 5-7 days.
• In case of acute intoxication with antipsychotic drugs – 50-300 mg / day intravenously for 7-14 days.

Overdose
Overdose symptoms: increased blood pressure, sleep disturbance, drowsiness.
Treatment is symptomatic, detoxification therapy is performed.

Side effects:

• Cardiovascular disorders: decrease / increase in blood pressure, palpitation, tachycardia.
• Neurological disorders: disturbances in the process of falling asleep, drowsiness, anxiety, headaches, emotional reactivity, impaired coordination.
• Digestive disorders: dry mouth, nausea, flatulence.
• Immune disorders: manifestations of allergies, including skin rashes, urticaria, angioedema, itching.
• Others: distal hyperhidrosis, metallic taste, sensation of heat, sore throat, discomfort behind the breastbone, shortness of breath, tremor, facial flushing, peripheral edema.

Storage conditions and periods
Store Mexicor in its original packaging at a temperature not exceeding + 25 ° C. The maximum shelf life is three years from the date of production.