Mildronat (meldonium dihydrate) hard capsules 250 mg. №40

Description

Mildronat composition       
active substance: meldonium;
1 hard capsule contains 250 mg of meldonium;
excipients: potato starch, silicon dioxide, calcium stearate.

Dosage form
The capsules are hard.

Pharmacological properties
It is a remedy that improves metabolic processes. The drug restores the balance between the need for oxygen and its delivery to the cells, eliminates the accumulated toxic products of cellular metabolism. Also has a tonic effect. In the case of heart failure, it increases the contractility of the myocardium, reduces the incidence of angina attacks, and increases exercise tolerance. In case of cerebral circulation ischemic disorders, it improves blood flow in the ischemic focus, promotes blood redistribution in favor of the area suffering from a lack of oxygen. The drug helps to eliminate functional disorders of the nervous system.

Indications
Mildronat is prescribed in complex therapy:

• with ischemic heart disease (including angina pectoris, myocardial infarction);
• with reduced performance or physical overstrain (for example, y athletes);
• with chronic heart failure;
• with dyshormonal cardiomyopathy;
• with acute / chronic disorders of cerebral blood supply (stroke, cerebrovascular insufficiency);
• with thrombosis of the central retinal vein, its branches;
• with hemophthalmos (vitreous hemorrhage);
• with retinal hemorrhage;
• with retinopathy (diabetic, hypertensive);
• with withdrawal syndrome (in the complex treatment of alcoholism).

Contraindications
Mildronat should not be prescribed:

• with intolerance to the components;
• with increased intracranial pressure (with impaired venous outflow, the growth of intracranial tumors).

Children
There is no data on the safety and efficacy of using meldonium for children (under the age of 18), therefore, the use of meldonium in this category of patients is contraindicated.

Application during pregnancy or lactation
The potential risk to humans is unknown, therefore meldonium is contraindicated during pregnancy.
The risk to newborns / babies cannot be ruled out, therefore meldonium is contraindicated during breastfeeding.

Method of administration and dosage
Apply orally before or after meals. The capsule is swallowed with water. Due to the possible stimulating effect, the drug is recommended to be used in the morning.
Diseases of the heart and circulatory system, disorders of cerebral circulation
The daily dose is 500-1000 mg per day. You can apply the entire dose in one dose or divide it by 2 times. The maximum daily dose is 1000 mg.
Reduced performance, overexertion, and convalescence
The daily dose is 500 mg per day. The maximum daily dose is 500 mg.
The duration of the course of treatment is 4-6 weeks. The course of treatment can be repeated 2-3 times a year.

Overdose
Overdose cases are not known. The drug is low-toxic and does not cause adverse reactions dangerous to human health, even in case of an overdose.

Side effects
Possible tachycardia, agitation, fluctuations in blood pressure, allergic reactions (exanthema, angioedema, urticaria, shock), dyspeptic symptoms.

Storage conditions and periods
Mildronat must be stored in its original packaging for no more than 2 years.
Temperature range: within 15-25 ° C. Protect from moisture.
Parents have a responsibility to ensure the safety of children by limiting their access to medicine.