Description

Nalbuk Solution for Injections 10 mg/ml. 2 ml. Ampoules №5

Ingredients:

Each 2 ml ampoule contains 10 mg of Nalbuphine hydrochloride as the active ingredient.

Dosage:

The usual adult dose is 10 mg to 20 mg administered intramuscularly every 3 to 6 hours as needed for pain relief.

Indications:

Nalbuk Solution is indicated for the relief of moderate to severe pain. It is commonly used postoperatively, during labor, and in patients with acute or chronic pain conditions.

Contraindications:

Do not use Nalbuk Solution in patients with a known hypersensitivity to nalbuphine or any of the ingredients in the formulation. It should also be avoided in patients with a history of substance abuse.

Directions:

Administer Nalbuk Solution via deep intramuscular injection. Avoid intravenous administration. The injection site should be rotated to prevent tissue irritation.

Scientific Evidence:

Nalbuphine, the active ingredient in Nalbuk Solution, is a semi-synthetic opioid analgesic with agonist and antagonist properties. It acts on the mu and kappa opioid receptors in the central nervous system, providing analgesic effects while reducing the risk of respiratory depression compared to pure mu agonists.

Additional Information:

Nalbuk Solution offers a balanced analgesic effect suitable for various pain conditions. Clinical trials have shown its efficacy in managing postoperative pain with a lower incidence of side effects compared to traditional opioids.

Research published in the Journal of Pain Research demonstrated the effectiveness of nalbuphine in providing pain relief in patients with acute pain, highlighting its potential as a valuable analgesic option in clinical practice.