Description

Nazivin (oxymetazoline) Nasal Spray 0.05% 10 ml

Ingredients:

Each 1 ml contains 0.5 mg of oxymetazoline hydrochloride as the active ingredient. Other ingredients include benzalkonium chloride, disodium edetate, sodium dihydrogen phosphate dihydrate, sodium monohydrogen phosphate dihydrate, sorbitol, and purified water.

Dosage:

For adults and children over 6 years: 1-2 sprays into each nostril every 10-12 hours. Do not exceed 2 doses in 24 hours.

Indications:

Nazivin Nasal Spray is indicated for the relief of nasal congestion associated with allergies, hay fever, sinusitis, and the common cold. It works by constricting blood vessels in the nasal passages, reducing swelling and congestion.

Contraindications:

Do not use Nazivin Nasal Spray if you are allergic to oxymetazoline or any other ingredients in the product. Avoid use in patients with narrow-angle glaucoma or severe heart disease.

Directions:

Shake well before use. Tilt head slightly forward, insert nozzle into nostril, and spray while breathing in gently. Repeat for the other nostril. Avoid spraying into eyes or mouth. Do not use for more than 3 consecutive days.

Scientific Evidence:

Oxymetazoline, the active ingredient in Nazivin Nasal Spray, has been extensively studied for its efficacy in relieving nasal congestion. Research published in the Journal of Allergy and Clinical Immunology has shown that oxymetazoline provides rapid and long-lasting relief of nasal congestion compared to placebo.

Additional Information:

It is important to note that prolonged use of nasal decongestants like oxymetazoline can lead to rebound congestion when the medication is stopped. To avoid this, limit the use of Nazivin Nasal Spray to 3 days or as directed by a healthcare provider. If symptoms persist, consult a doctor.

Pharmacological Effects: Oxymetazoline acts as a selective alpha-1 adrenergic receptor agonist, causing vasoconstriction in the nasal mucosa. This action reduces swelling and congestion, allowing for easier breathing.

Clinical Trials: A randomized controlled trial published in the American Journal of Rhinology & Allergy demonstrated the superior efficacy of oxymetazoline nasal spray in improving nasal airflow and congestion compared to saline solution.