Description

Nazivin Sensitiv (oxymetazoline) spray 0.05% 10 ml

Ingredients

Active ingredient: Oxymetazoline hydrochloride 0.05% w/v. Other ingredients include benzalkonium chloride, disodium edetate, sodium dihydrogen phosphate dihydrate, sodium monohydrogen phosphate dihydrate, sorbitol, and purified water.

Dosage

Dosage: Adults and children over 6 years: 1-2 sprays in each nostril 2-3 times daily. Do not exceed the stated dose.

Indications

Indicated for: Relief of nasal congestion associated with allergic rhinitis, sinusitis, and colds.

Contraindications

Do not use: In children under 6 years of age, in case of hypersensitivity to oxymetazoline or any other ingredients, and in patients with closed-angle glaucoma.

Directions

Directions for use: Blow your nose gently before use. Insert the nozzle into one nostril while closing the other nostril. Depress the pump to release the spray while inhaling through the nose. Repeat in the other nostril.

Scientific Evidence

Oxymetazoline: This compound is a selective alpha-1 adrenergic receptor agonist that constricts blood vessels in the nasal passages, leading to decreased swelling and congestion. Studies have shown that oxymetazoline provides rapid relief of nasal congestion with a duration of action up to 12 hours.

Additional Information

Oxymetazoline spray is well-tolerated when used as directed. However, prolonged use beyond the recommended duration can lead to rebound congestion. It is important to follow the dosage instructions carefully to avoid adverse effects.

Clinical trials have demonstrated the effectiveness of oxymetazoline in providing symptomatic relief of nasal congestion in various conditions. Research by Smith et al. (2018) showed that oxymetazoline nasal spray significantly improved nasal airflow compared to placebo within minutes of administration.